Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1546301..1546886 Replicon chromosome
Accession NZ_CP118154
Organism Pseudomonas chlororaphis strain ATCC 17414

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP71_RS06805 Protein ID WP_053260473.1
Coordinates 1546301..1546594 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP71_RS06810 Protein ID WP_053260472.1
Coordinates 1546596..1546886 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP71_RS06785 (PUP71_06785) 1541318..1541713 - 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -
PUP71_RS06790 (PUP71_06790) 1541946..1543190 - 1245 WP_053260476.1 M20/M25/M40 family metallo-hydrolase -
PUP71_RS06795 (PUP71_06795) 1543284..1544408 - 1125 WP_053260475.1 diguanylate cyclase -
PUP71_RS06800 (PUP71_06800) 1544672..1546066 + 1395 WP_053260474.1 VOC family protein -
PUP71_RS06805 (PUP71_06805) 1546301..1546594 + 294 WP_053260473.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP71_RS06810 (PUP71_06810) 1546596..1546886 + 291 WP_053260472.1 putative addiction module antidote protein Antitoxin
PUP71_RS06815 (PUP71_06815) 1547283..1547870 - 588 WP_053260471.1 hypothetical protein -
PUP71_RS06820 (PUP71_06820) 1547989..1549371 - 1383 WP_053260470.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10846.56 Da        Isoelectric Point: 10.5107

>T272890 WP_053260473.1 NZ_CP118154:1546301-1546594 [Pseudomonas chlororaphis]
MNYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRLYFTVRGNTLIVLLLGGDK
STQPADICQARYLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10197.74 Da        Isoelectric Point: 8.0096

>AT272890 WP_053260472.1 NZ_CP118154:1546596-1546886 [Pseudomonas chlororaphis]
MSDTLLAFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References