Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6628367..6628956 Replicon chromosome
Accession NZ_CP118153
Organism Pseudomonas chlororaphis strain ATCC 17811

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP50_RS30280 Protein ID WP_007924097.1
Coordinates 6628657..6628956 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP50_RS30275 Protein ID WP_007924096.1
Coordinates 6628367..6628660 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP50_RS30250 (PUP50_30250) 6624076..6624534 + 459 WP_053262808.1 GNAT family N-acetyltransferase -
PUP50_RS30255 (PUP50_30255) 6624788..6625444 + 657 WP_007924093.1 DedA family protein -
PUP50_RS30260 (PUP50_30260) 6625450..6626259 + 810 WP_053262809.1 zinc-dependent peptidase -
PUP50_RS30265 (PUP50_30265) 6626524..6627051 + 528 WP_003228599.1 inorganic diphosphatase -
PUP50_RS30270 (PUP50_30270) 6627859..6628251 + 393 WP_274304786.1 hypothetical protein -
PUP50_RS30275 (PUP50_30275) 6628367..6628660 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
PUP50_RS30280 (PUP50_30280) 6628657..6628956 - 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP50_RS30285 (PUP50_30285) 6629128..6629577 + 450 WP_274304787.1 DUF3828 domain-containing protein -
PUP50_RS30290 (PUP50_30290) 6629602..6630612 - 1011 WP_185057585.1 NAD(P)-dependent alcohol dehydrogenase -
PUP50_RS30295 (PUP50_30295) 6630670..6630969 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP50_RS30300 (PUP50_30300) 6631037..6632125 - 1089 WP_274304788.1 copper-containing nitrite reductase -
PUP50_RS30305 (PUP50_30305) 6632352..6632594 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP50_RS30310 (PUP50_30310) 6632591..6633478 + 888 WP_274304789.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 6404116..6646014 241898


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T272889 WP_007924097.1 NZ_CP118153:c6628956-6628657 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT272889 WP_007924096.1 NZ_CP118153:c6628660-6628367 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References