Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2810675..2811260 Replicon chromosome
Accession NZ_CP118153
Organism Pseudomonas chlororaphis strain ATCC 17811

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP50_RS13185 Protein ID WP_274306290.1
Coordinates 2810967..2811260 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A285IMN7
Locus tag PUP50_RS13180 Protein ID WP_009043099.1
Coordinates 2810675..2810965 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP50_RS13170 (PUP50_13170) 2808189..2809571 + 1383 WP_274306289.1 efflux transporter outer membrane subunit -
PUP50_RS13175 (PUP50_13175) 2809690..2810277 + 588 WP_007923530.1 hypothetical protein -
PUP50_RS13180 (PUP50_13180) 2810675..2810965 - 291 WP_009043099.1 putative addiction module antidote protein Antitoxin
PUP50_RS13185 (PUP50_13185) 2810967..2811260 - 294 WP_274306290.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP50_RS13190 (PUP50_13190) 2811496..2812890 - 1395 WP_274306291.1 VOC family protein -
PUP50_RS13195 (PUP50_13195) 2813155..2814279 + 1125 WP_274306292.1 diguanylate cyclase -
PUP50_RS13200 (PUP50_13200) 2814373..2815617 + 1245 WP_053260476.1 M20/M25/M40 family metallo-hydrolase -
PUP50_RS13205 (PUP50_13205) 2815850..2816245 + 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10706.31 Da        Isoelectric Point: 10.0960

>T272888 WP_274306290.1 NZ_CP118153:c2811260-2810967 [Pseudomonas chlororaphis]
MDYEILQTAVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGHTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10223.78 Da        Isoelectric Point: 8.0096

>AT272888 WP_009043099.1 NZ_CP118153:c2810965-2810675 [Pseudomonas chlororaphis]
MSDTLLPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A285IMN7

References