Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2678311..2678981 Replicon chromosome
Accession NZ_CP118152
Organism Pseudomonas chlororaphis strain ATCC 336631

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP64_RS12285 Protein ID WP_081362979.1
Coordinates 2678553..2678981 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag PUP64_RS12280 Protein ID WP_009046453.1
Coordinates 2678311..2678556 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP64_RS12260 (PUP64_12260) 2674401..2675378 + 978 WP_081362975.1 taurine ABC transporter substrate-binding protein -
PUP64_RS12265 (PUP64_12265) 2675474..2676268 + 795 WP_081362976.1 taurine ABC transporter ATP-binding subunit -
PUP64_RS12270 (PUP64_12270) 2676265..2677104 + 840 WP_081362977.1 taurine ABC transporter permease TauC -
PUP64_RS12275 (PUP64_12275) 2677332..2678171 + 840 WP_081362978.1 taurine dioxygenase -
PUP64_RS12280 (PUP64_12280) 2678311..2678556 + 246 WP_009046453.1 plasmid stabilization protein Antitoxin
PUP64_RS12285 (PUP64_12285) 2678553..2678981 + 429 WP_081362979.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP64_RS12290 (PUP64_12290) 2679110..2680147 - 1038 WP_081362980.1 L-glyceraldehyde 3-phosphate reductase -
PUP64_RS12295 (PUP64_12295) 2680232..2681557 - 1326 WP_081362981.1 LLM class flavin-dependent oxidoreductase -
PUP64_RS12300 (PUP64_12300) 2681604..2683862 - 2259 WP_081362982.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15853.36 Da        Isoelectric Point: 5.4927

>T272881 WP_081362979.1 NZ_CP118152:2678553-2678981 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASAVAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT272881 WP_009046453.1 NZ_CP118152:2678311-2678556 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References