Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5708799..5709388 Replicon chromosome
Accession NZ_CP118151
Organism Pseudomonas chlororaphis strain ATCC 9446

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP54_RS25970 Protein ID WP_007924097.1
Coordinates 5709089..5709388 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP54_RS25965 Protein ID WP_009045810.1
Coordinates 5708799..5709092 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP54_RS25940 (PUP54_25940) 5704514..5704972 + 459 WP_053262808.1 GNAT family N-acetyltransferase -
PUP54_RS25945 (PUP54_25945) 5705226..5705882 + 657 WP_007924093.1 DedA family protein -
PUP54_RS25950 (PUP54_25950) 5705888..5706697 + 810 WP_053262809.1 zinc-dependent peptidase -
PUP54_RS25955 (PUP54_25955) 5706962..5707489 + 528 WP_003228599.1 inorganic diphosphatase -
PUP54_RS25960 (PUP54_25960) 5708297..5708683 + 387 WP_053262810.1 hypothetical protein -
PUP54_RS25965 (PUP54_25965) 5708799..5709092 - 294 WP_009045810.1 putative addiction module antidote protein Antitoxin
PUP54_RS25970 (PUP54_25970) 5709089..5709388 - 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP54_RS25975 (PUP54_25975) 5709560..5710009 + 450 WP_053262811.1 DUF3828 domain-containing protein -
PUP54_RS25980 (PUP54_25980) 5710034..5711044 - 1011 WP_173613368.1 NAD(P)-dependent alcohol dehydrogenase -
PUP54_RS25985 (PUP54_25985) 5711102..5711401 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP54_RS25990 (PUP54_25990) 5711468..5712556 - 1089 WP_053262813.1 copper-containing nitrite reductase -
PUP54_RS25995 (PUP54_25995) 5712783..5713025 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP54_RS26000 (PUP54_26000) 5713022..5713909 + 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T272878 WP_007924097.1 NZ_CP118151:c5709388-5709089 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT272878 WP_009045810.1 NZ_CP118151:c5709092-5708799 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References