Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2090592..2091177 Replicon chromosome
Accession NZ_CP118151
Organism Pseudomonas chlororaphis strain ATCC 9446

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP54_RS09775 Protein ID WP_053260473.1
Coordinates 2090884..2091177 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP54_RS09770 Protein ID WP_053260472.1
Coordinates 2090592..2090882 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP54_RS09760 (PUP54_09760) 2088107..2089489 + 1383 WP_053260470.1 efflux transporter outer membrane subunit -
PUP54_RS09765 (PUP54_09765) 2089608..2090195 + 588 WP_053260471.1 hypothetical protein -
PUP54_RS09770 (PUP54_09770) 2090592..2090882 - 291 WP_053260472.1 putative addiction module antidote protein Antitoxin
PUP54_RS09775 (PUP54_09775) 2090884..2091177 - 294 WP_053260473.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP54_RS09780 (PUP54_09780) 2091412..2092806 - 1395 WP_053260474.1 VOC family protein -
PUP54_RS09785 (PUP54_09785) 2093070..2094194 + 1125 WP_053260475.1 diguanylate cyclase -
PUP54_RS09790 (PUP54_09790) 2094288..2095532 + 1245 WP_053260476.1 M20/M25/M40 family metallo-hydrolase -
PUP54_RS09795 (PUP54_09795) 2095765..2096160 + 396 WP_007932579.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10846.56 Da        Isoelectric Point: 10.5107

>T272877 WP_053260473.1 NZ_CP118151:c2091177-2090884 [Pseudomonas chlororaphis]
MNYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRLYFTVRGNTLIVLLLGGDK
STQPADICQARYLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10197.74 Da        Isoelectric Point: 8.0096

>AT272877 WP_053260472.1 NZ_CP118151:c2090882-2090592 [Pseudomonas chlororaphis]
MSDTLLAFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References