Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 658242..658780 Replicon chromosome
Accession NZ_CP118151
Organism Pseudomonas chlororaphis strain ATCC 9446

Toxin (Protein)


Gene name relE Uniprot ID A0A285H8D2
Locus tag PUP54_RS02860 Protein ID WP_009042149.1
Coordinates 658502..658780 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP54_RS02855 Protein ID WP_053259626.1
Coordinates 658242..658505 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP54_RS02840 (PUP54_02840) 654231..656504 - 2274 WP_053259624.1 TonB-dependent siderophore receptor -
PUP54_RS02845 (PUP54_02845) 656711..657391 + 681 WP_009042146.1 Fe2+-dependent dioxygenase -
PUP54_RS02850 (PUP54_02850) 657395..658180 + 786 WP_053259625.1 tetratricopeptide repeat protein -
PUP54_RS02855 (PUP54_02855) 658242..658505 + 264 WP_053259626.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP54_RS02860 (PUP54_02860) 658502..658780 + 279 WP_009042149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP54_RS02865 (PUP54_02865) 658855..660018 - 1164 WP_009042150.1 type III PLP-dependent enzyme -
PUP54_RS02870 (PUP54_02870) 660718..661875 - 1158 WP_007923834.1 ABC transporter ATP-binding protein -
PUP54_RS02875 (PUP54_02875) 661872..662525 - 654 WP_053259627.1 ABC transporter permease -
PUP54_RS02880 (PUP54_02880) 662540..663433 - 894 WP_053259628.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10853.45 Da        Isoelectric Point: 8.5409

>T272875 WP_009042149.1 NZ_CP118151:658502-658780 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9769.19 Da        Isoelectric Point: 5.6088

>AT272875 WP_053259626.1 NZ_CP118151:658242-658505 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDVGRVIDHQAVQAWAESLMSD
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285H8D2

Antitoxin

Source ID Structure

References