272874

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6504966..6505555 Replicon chromosome
Accession NZ_CP118150
Organism Pseudomonas chlororaphis strain DSM 21509

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP49_RS29375 Protein ID WP_016702674.1
Coordinates 6505256..6505555 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP49_RS29370 Protein ID WP_053281098.1
Coordinates 6504966..6505259 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP49_RS29345 (PUP49_29345) 6500601..6501329 + 729 WP_053281093.1 ABC transporter permease -
PUP49_RS29350 (PUP49_29350) 6501326..6502036 + 711 WP_053281094.1 ABC transporter permease -
PUP49_RS29355 (PUP49_29355) 6502053..6502817 + 765 WP_053281095.1 ATP-binding cassette domain-containing protein -
PUP49_RS29360 (PUP49_29360) 6503204..6503596 + 393 WP_053281096.1 DUF3077 domain-containing protein -
PUP49_RS29365 (PUP49_29365) 6503797..6504960 + 1164 WP_053281097.1 GGDEF domain-containing protein -
PUP49_RS29370 (PUP49_29370) 6504966..6505259 - 294 WP_053281098.1 putative addiction module antidote protein Antitoxin
PUP49_RS29375 (PUP49_29375) 6505256..6505555 - 300 WP_016702674.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP49_RS29380 (PUP49_29380) 6505728..6506177 + 450 WP_053281099.1 DUF3828 domain-containing protein -
PUP49_RS29385 (PUP49_29385) 6506202..6507212 - 1011 WP_172833187.1 NAD(P)-dependent alcohol dehydrogenase -
PUP49_RS29390 (PUP49_29390) 6507268..6507567 - 300 WP_053281101.1 helix-turn-helix transcriptional regulator -
PUP49_RS29395 (PUP49_29395) 6507634..6508722 - 1089 WP_053281102.1 copper-containing nitrite reductase -
PUP49_RS29400 (PUP49_29400) 6508950..6509192 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP49_RS29405 (PUP49_29405) 6509189..6510076 + 888 WP_053281103.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11221.93 Da        Isoelectric Point: 10.6086

>T272874 WP_016702674.1 NZ_CP118150:c6505555-6505256 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10584.16 Da        Isoelectric Point: 6.4627

>AT272874 WP_053281098.1 NZ_CP118150:c6505259-6504966 [Pseudomonas chlororaphis]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHVRP

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References