Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2603855..2604440 Replicon chromosome
Accession NZ_CP118150
Organism Pseudomonas chlororaphis strain DSM 21509

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP49_RS12045 Protein ID WP_053278359.1
Coordinates 2604147..2604440 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP49_RS12040 Protein ID WP_053278358.1
Coordinates 2603855..2604145 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP49_RS12025 (PUP49_12025) 2599180..2601660 + 2481 WP_053278594.1 FtsX-like permease family protein -
PUP49_RS12030 (PUP49_12030) 2601650..2602726 + 1077 WP_053278356.1 lipocalin-like domain-containing protein -
PUP49_RS12035 (PUP49_12035) 2602854..2603441 + 588 WP_053278357.1 hypothetical protein -
PUP49_RS12040 (PUP49_12040) 2603855..2604145 - 291 WP_053278358.1 putative addiction module antidote protein Antitoxin
PUP49_RS12045 (PUP49_12045) 2604147..2604440 - 294 WP_053278359.1 addiction module antitoxin RelB Toxin
PUP49_RS12050 (PUP49_12050) 2604676..2606070 - 1395 WP_053278360.1 VOC family protein -
PUP49_RS12055 (PUP49_12055) 2606333..2607457 + 1125 WP_053278361.1 diguanylate cyclase -
PUP49_RS12060 (PUP49_12060) 2607551..2608795 + 1245 WP_053278362.1 M20/M25/M40 family metallo-hydrolase -
PUP49_RS12065 (PUP49_12065) 2609003..2609401 + 399 WP_053278363.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10812.46 Da        Isoelectric Point: 10.7340

>T272872 WP_053278359.1 NZ_CP118150:c2604440-2604147 [Pseudomonas chlororaphis]
MDYEIQQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSQMRVNMGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10219.79 Da        Isoelectric Point: 8.0096

>AT272872 WP_053278358.1 NZ_CP118150:c2604145-2603855 [Pseudomonas chlororaphis]
MSDTLVPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References