272860

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6360120..6360709 Replicon chromosome
Accession NZ_CP118148
Organism Pseudomonas chlororaphis strain NCCB 880622

Toxin (Protein)


Gene name PumA Uniprot ID A0A554PHZ9
Locus tag PUP58_RS28720 Protein ID WP_041987451.1
Coordinates 6360410..6360709 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP58_RS28715 Protein ID WP_041987449.1
Coordinates 6360120..6360413 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP58_RS28695 (PUP58_28695) 6355661..6356824 - 1164 WP_041987444.1 acyltransferase -
PUP58_RS28700 (PUP58_28700) 6357019..6358209 - 1191 WP_041987447.1 serine hydrolase domain-containing protein -
PUP58_RS28705 (PUP58_28705) 6358336..6359223 + 888 WP_009051074.1 LysR family transcriptional regulator -
PUP58_RS28710 (PUP58_28710) 6359595..6359987 + 393 WP_009051075.1 hypothetical protein -
PUP58_RS28715 (PUP58_28715) 6360120..6360413 - 294 WP_041987449.1 putative addiction module antidote protein Antitoxin
PUP58_RS28720 (PUP58_28720) 6360410..6360709 - 300 WP_041987451.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP58_RS28725 (PUP58_28725) 6360880..6361329 + 450 WP_124314409.1 DUF3828 domain-containing protein -
PUP58_RS28730 (PUP58_28730) 6361354..6362364 - 1011 WP_173424526.1 NAD(P)-dependent alcohol dehydrogenase -
PUP58_RS28735 (PUP58_28735) 6362422..6362721 - 300 WP_009051080.1 helix-turn-helix transcriptional regulator -
PUP58_RS28740 (PUP58_28740) 6362785..6363876 - 1092 WP_009051081.1 copper-containing nitrite reductase -
PUP58_RS28745 (PUP58_28745) 6364102..6364344 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP58_RS28750 (PUP58_28750) 6364341..6365228 + 888 WP_009051083.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11231.97 Da        Isoelectric Point: 10.6086

>T272860 WP_041987451.1 NZ_CP118148:c6360709-6360410 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10446.94 Da        Isoelectric Point: 5.6558

>AT272860 WP_041987449.1 NZ_CP118148:c6360413-6360120 [Pseudomonas chlororaphis]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554PHZ9

Antitoxin

Source ID Structure

References