272856

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 543927..544597 Replicon chromosome
Accession NZ_CP118148
Organism Pseudomonas chlororaphis strain NCCB 880622

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP58_RS02445 Protein ID WP_009046452.1
Coordinates 543927..544355 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag PUP58_RS02450 Protein ID WP_009046453.1
Coordinates 544352..544597 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP58_RS02415 (PUP58_02415) 539149..539658 - 510 WP_274319199.1 DUF1097 domain-containing protein -
PUP58_RS02420 (PUP58_02420) 539692..540432 - 741 WP_274319200.1 SDR family oxidoreductase -
PUP58_RS02425 (PUP58_02425) 540562..541452 + 891 WP_041985374.1 LysR family transcriptional regulator -
PUP58_RS02430 (PUP58_02430) 541577..541759 + 183 WP_009041685.1 type II toxin-antitoxin system HicA family toxin -
PUP58_RS02435 (PUP58_02435) 541789..542190 + 402 WP_009046450.1 type II toxin-antitoxin system HicB family antitoxin -
PUP58_RS02440 (PUP58_02440) 542760..543797 + 1038 WP_124314665.1 L-glyceraldehyde 3-phosphate reductase -
PUP58_RS02445 (PUP58_02445) 543927..544355 - 429 WP_009046452.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP58_RS02450 (PUP58_02450) 544352..544597 - 246 WP_009046453.1 plasmid stabilization protein Antitoxin
PUP58_RS02455 (PUP58_02455) 544737..545576 - 840 WP_009046454.1 taurine dioxygenase -
PUP58_RS02460 (PUP58_02460) 545812..546651 - 840 WP_009046455.1 taurine ABC transporter permease TauC -
PUP58_RS02465 (PUP58_02465) 546648..547442 - 795 WP_028683844.1 taurine ABC transporter ATP-binding subunit -
PUP58_RS02470 (PUP58_02470) 547538..548515 - 978 WP_009046457.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15867.39 Da        Isoelectric Point: 5.4927

>T272856 WP_009046452.1 NZ_CP118148:c544355-543927 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASALAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT272856 WP_009046453.1 NZ_CP118148:c544597-544352 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References