272854

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 430407..430923 Replicon chromosome
Accession NZ_CP118148
Organism Pseudomonas chlororaphis strain NCCB 880622

Toxin (Protein)


Gene name stbE Uniprot ID A0A8A9Z863
Locus tag PUP58_RS01915 Protein ID WP_028681510.1
Coordinates 430642..430923 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag PUP58_RS01910 Protein ID WP_009046356.1
Coordinates 430407..430652 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP58_RS01885 (PUP58_01885) 426175..427170 + 996 WP_124301006.1 sulfotransferase family protein -
PUP58_RS01890 (PUP58_01890) 427136..427894 - 759 WP_009046352.1 slipin family protein -
PUP58_RS01895 (PUP58_01895) 427896..429281 - 1386 WP_009046353.1 nodulation protein NfeD -
PUP58_RS01900 (PUP58_01900) 429505..429966 + 462 WP_016705004.1 YbaK/EbsC family protein -
PUP58_RS01905 (PUP58_01905) 430097..430342 + 246 WP_009046355.1 DUF2789 domain-containing protein -
PUP58_RS01910 (PUP58_01910) 430407..430652 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP58_RS01915 (PUP58_01915) 430642..430923 + 282 WP_028681510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP58_RS01920 (PUP58_01920) 431056..431484 + 429 WP_009046358.1 MarR family transcriptional regulator -
PUP58_RS01925 (PUP58_01925) 431481..433565 + 2085 WP_274319182.1 FUSC family protein -
PUP58_RS01930 (PUP58_01930) 433562..433771 + 210 WP_007932080.1 DUF1656 domain-containing protein -
PUP58_RS01935 (PUP58_01935) 433768..434664 + 897 WP_016705006.1 HlyD family secretion protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10907.82 Da        Isoelectric Point: 10.6258

>T272854 WP_028681510.1 NZ_CP118148:430642-430923 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKRKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp


Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT272854 WP_009046356.1 NZ_CP118148:430407-430652 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A8A9Z863


Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References