Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6111882..6112471 Replicon chromosome
Accession NZ_CP118147
Organism Pseudomonas chlororaphis strain ATCC 174151

Toxin (Protein)


Gene name PumA Uniprot ID A0A285IHJ3
Locus tag PUP56_RS27570 Protein ID WP_062824477.1
Coordinates 6112172..6112471 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP56_RS27565 Protein ID WP_007924096.1
Coordinates 6111882..6112175 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP56_RS27540 (PUP56_27540) 6107595..6108053 + 459 WP_009045805.1 GNAT family N-acetyltransferase -
PUP56_RS27545 (PUP56_27545) 6108307..6108963 + 657 WP_007924093.1 DedA family protein -
PUP56_RS27550 (PUP56_27550) 6108969..6109778 + 810 WP_062824480.1 zinc-dependent peptidase -
PUP56_RS27555 (PUP56_27555) 6110043..6110570 + 528 WP_114761534.1 inorganic diphosphatase -
PUP56_RS27560 (PUP56_27560) 6111385..6111766 + 382 Protein_5431 DUF3077 domain-containing protein -
PUP56_RS27565 (PUP56_27565) 6111882..6112175 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
PUP56_RS27570 (PUP56_27570) 6112172..6112471 - 300 WP_062824477.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP56_RS27575 (PUP56_27575) 6112643..6113092 + 450 WP_009045812.1 DUF3828 domain-containing protein -
PUP56_RS27580 (PUP56_27580) 6113117..6114127 - 1011 WP_205350727.1 NAD(P)-dependent alcohol dehydrogenase -
PUP56_RS27585 (PUP56_27585) 6114185..6114484 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP56_RS27590 (PUP56_27590) 6114552..6115640 - 1089 WP_062824475.1 copper-containing nitrite reductase -
PUP56_RS27595 (PUP56_27595) 6115866..6116108 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP56_RS27600 (PUP56_27600) 6116105..6116992 + 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11261.01 Da        Isoelectric Point: 10.8652

>T272853 WP_062824477.1 NZ_CP118147:c6112471-6112172 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQGRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT272853 WP_007924096.1 NZ_CP118147:c6112175-6111882 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285IHJ3

Antitoxin

Source ID Structure

References