Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 570236..570906 Replicon chromosome
Accession NZ_CP118146
Organism Pseudomonas chlororaphis strain ATCC 174152

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP66_RS02555 Protein ID WP_062824000.1
Coordinates 570236..570664 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N8BIH3
Locus tag PUP66_RS02560 Protein ID WP_062823999.1
Coordinates 570661..570906 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP66_RS02540 (PUP66_02540) 565358..567616 + 2259 WP_114760181.1 TonB-dependent receptor -
PUP66_RS02545 (PUP66_02545) 567663..568988 + 1326 WP_009041689.1 LLM class flavin-dependent oxidoreductase -
PUP66_RS02550 (PUP66_02550) 569073..570110 + 1038 WP_114760182.1 L-glyceraldehyde 3-phosphate reductase -
PUP66_RS02555 (PUP66_02555) 570236..570664 - 429 WP_062824000.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP66_RS02560 (PUP66_02560) 570661..570906 - 246 WP_062823999.1 hypothetical protein Antitoxin
PUP66_RS02565 (PUP66_02565) 571034..571873 - 840 WP_097134161.1 taurine dioxygenase -
PUP66_RS02570 (PUP66_02570) 572057..572896 - 840 WP_114760183.1 taurine ABC transporter permease TauC -
PUP66_RS02575 (PUP66_02575) 572893..573687 - 795 WP_114760184.1 taurine ABC transporter ATP-binding subunit -
PUP66_RS02580 (PUP66_02580) 573783..574760 - 978 WP_009041696.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15811.42 Da        Isoelectric Point: 5.4927

>T272842 WP_062824000.1 NZ_CP118146:c570664-570236 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQMLHASALAMFEEDFIDRIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9129.35 Da        Isoelectric Point: 7.3226

>AT272842 WP_062823999.1 NZ_CP118146:c570906-570661 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALNRTTDSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8BIH3

References