Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2551660..2552245 Replicon chromosome
Accession NZ_CP118145
Organism Pseudomonas chlororaphis strain ATCC 17417

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP75_RS11730 Protein ID WP_085530375.1
Coordinates 2551952..2552245 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A285IMN7
Locus tag PUP75_RS11725 Protein ID WP_009043099.1
Coordinates 2551660..2551950 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP75_RS11715 (PUP75_11715) 2549175..2550557 + 1383 WP_062822916.1 efflux transporter outer membrane subunit -
PUP75_RS11720 (PUP75_11720) 2550676..2551263 + 588 WP_007923530.1 hypothetical protein -
PUP75_RS11725 (PUP75_11725) 2551660..2551950 - 291 WP_009043099.1 putative addiction module antidote protein Antitoxin
PUP75_RS11730 (PUP75_11730) 2551952..2552245 - 294 WP_085530375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP75_RS11735 (PUP75_11735) 2552481..2553875 - 1395 WP_274336213.1 VOC family protein -
PUP75_RS11740 (PUP75_11740) 2554140..2555264 + 1125 WP_274336214.1 diguanylate cyclase -
PUP75_RS11745 (PUP75_11745) 2555358..2556602 + 1245 WP_274336215.1 M20/M25/M40 family metallo-hydrolase -
PUP75_RS11750 (PUP75_11750) 2556834..2557229 + 396 WP_114761931.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10736.34 Da        Isoelectric Point: 10.0960

>T272839 WP_085530375.1 NZ_CP118145:c2552245-2551952 [Pseudomonas chlororaphis]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGHTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10223.78 Da        Isoelectric Point: 8.0096

>AT272839 WP_009043099.1 NZ_CP118145:c2551950-2551660 [Pseudomonas chlororaphis]
MSDTLLPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A285IMN7

References