272836

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1215087..1215625 Replicon chromosome
Accession NZ_CP118145
Organism Pseudomonas chlororaphis strain ATCC 17417

Toxin (Protein)


Gene name relE Uniprot ID A0A285H8D2
Locus tag PUP75_RS05380 Protein ID WP_009042149.1
Coordinates 1215347..1215625 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP75_RS05375 Protein ID WP_009042148.1
Coordinates 1215087..1215350 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP75_RS05360 (PUP75_05360) 1211076..1213349 - 2274 WP_009042145.1 TonB-dependent siderophore receptor -
PUP75_RS05365 (PUP75_05365) 1213557..1214237 + 681 WP_009042146.1 Fe2+-dependent dioxygenase -
PUP75_RS05370 (PUP75_05370) 1214241..1215026 + 786 WP_274335806.1 tetratricopeptide repeat protein -
PUP75_RS05375 (PUP75_05375) 1215087..1215350 + 264 WP_009042148.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP75_RS05380 (PUP75_05380) 1215347..1215625 + 279 WP_009042149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP75_RS05385 (PUP75_05385) 1215700..1216863 - 1164 WP_009042150.1 type III PLP-dependent enzyme -
PUP75_RS05390 (PUP75_05390) 1217401..1218558 - 1158 WP_274335807.1 ABC transporter ATP-binding protein -
PUP75_RS05395 (PUP75_05395) 1218555..1219208 - 654 WP_007923833.1 ABC transporter permease -
PUP75_RS05400 (PUP75_05400) 1219223..1220116 - 894 WP_274335808.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10853.45 Da        Isoelectric Point: 8.5409

>T272836 WP_009042149.1 NZ_CP118145:1215347-1215625 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9768.17 Da        Isoelectric Point: 5.6088

>AT272836 WP_009042148.1 NZ_CP118145:1215087-1215350 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGRVIDHQAVQAWAESLMND
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285H8D2

Antitoxin

Source ID Structure

References