Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 429911..430427 Replicon chromosome
Accession NZ_CP118145
Organism Pseudomonas chlororaphis strain ATCC 17417

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag PUP75_RS01920 Protein ID WP_009041601.1
Coordinates 430146..430427 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A285F0M2
Locus tag PUP75_RS01915 Protein ID WP_062824057.1
Coordinates 429911..430156 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP75_RS01890 (PUP75_01890) 425528..426529 + 1002 WP_274335567.1 sulfotransferase family protein -
PUP75_RS01895 (PUP75_01895) 426495..427253 - 759 WP_007932057.1 slipin family protein -
PUP75_RS01900 (PUP75_01900) 427255..428640 - 1386 WP_274335568.1 nodulation protein NfeD -
PUP75_RS01905 (PUP75_01905) 428864..429325 + 462 WP_062824058.1 YbaK/EbsC family protein -
PUP75_RS01910 (PUP75_01910) 429603..429848 + 246 WP_009041599.1 DUF2789 domain-containing protein -
PUP75_RS01915 (PUP75_01915) 429911..430156 + 246 WP_062824057.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP75_RS01920 (PUP75_01920) 430146..430427 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP75_RS01925 (PUP75_01925) 430559..430987 + 429 WP_085533251.1 MarR family transcriptional regulator -
PUP75_RS01930 (PUP75_01930) 430984..433068 + 2085 WP_274335569.1 FUSC family protein -
PUP75_RS01935 (PUP75_01935) 433065..433274 + 210 WP_007932080.1 DUF1656 domain-containing protein -
PUP75_RS01940 (PUP75_01940) 433271..434167 + 897 WP_274335570.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T272833 WP_009041601.1 NZ_CP118145:430146-430427 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8822.17 Da        Isoelectric Point: 5.0216

>AT272833 WP_062824057.1 NZ_CP118145:429911-430156 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLSGAHGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A285F0M2

References