Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6351716..6352305 Replicon chromosome
Accession NZ_CP118144
Organism Pseudomonas chlororaphis strain ATCC 174181

Toxin (Protein)


Gene name PumA Uniprot ID A0A285IHJ3
Locus tag PUP51_RS28715 Protein ID WP_062824477.1
Coordinates 6352006..6352305 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP51_RS28710 Protein ID WP_007924096.1
Coordinates 6351716..6352009 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP51_RS28685 (PUP51_28685) 6347452..6347910 + 459 WP_009045805.1 GNAT family N-acetyltransferase -
PUP51_RS28690 (PUP51_28690) 6348160..6348816 + 657 WP_007924093.1 DedA family protein -
PUP51_RS28695 (PUP51_28695) 6348822..6349631 + 810 WP_062824480.1 zinc-dependent peptidase -
PUP51_RS28700 (PUP51_28700) 6349896..6350423 + 528 WP_062824479.1 inorganic diphosphatase -
PUP51_RS28705 (PUP51_28705) 6351208..6351600 + 393 WP_274330603.1 hypothetical protein -
PUP51_RS28710 (PUP51_28710) 6351716..6352009 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
PUP51_RS28715 (PUP51_28715) 6352006..6352305 - 300 WP_062824477.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP51_RS28720 (PUP51_28720) 6352477..6352926 + 450 WP_009045812.1 DUF3828 domain-containing protein -
PUP51_RS28725 (PUP51_28725) 6352951..6353961 - 1011 WP_274333800.1 NAD(P)-dependent alcohol dehydrogenase -
PUP51_RS28730 (PUP51_28730) 6354019..6354318 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP51_RS28735 (PUP51_28735) 6354386..6355474 - 1089 WP_274330605.1 copper-containing nitrite reductase -
PUP51_RS28740 (PUP51_28740) 6355700..6355942 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP51_RS28745 (PUP51_28745) 6355939..6356826 + 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11261.01 Da        Isoelectric Point: 10.8652

>T272832 WP_062824477.1 NZ_CP118144:c6352305-6352006 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQGRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT272832 WP_007924096.1 NZ_CP118144:c6352009-6351716 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285IHJ3

Antitoxin

Source ID Structure

References