Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2598659..2599244 Replicon chromosome
Accession NZ_CP118144
Organism Pseudomonas chlororaphis strain ATCC 174181

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP51_RS11845 Protein ID WP_062822913.1
Coordinates 2598951..2599244 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A285IMN7
Locus tag PUP51_RS11840 Protein ID WP_009043099.1
Coordinates 2598659..2598949 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP51_RS11830 (PUP51_11830) 2596174..2597556 + 1383 WP_274332749.1 efflux transporter outer membrane subunit -
PUP51_RS11835 (PUP51_11835) 2597675..2598262 + 588 WP_274332750.1 hypothetical protein -
PUP51_RS11840 (PUP51_11840) 2598659..2598949 - 291 WP_009043099.1 putative addiction module antidote protein Antitoxin
PUP51_RS11845 (PUP51_11845) 2598951..2599244 - 294 WP_062822913.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP51_RS11850 (PUP51_11850) 2599480..2600874 - 1395 WP_123361693.1 VOC family protein -
PUP51_RS11855 (PUP51_11855) 2601139..2602263 + 1125 WP_274332755.1 diguanylate cyclase -
PUP51_RS11860 (PUP51_11860) 2602357..2603601 + 1245 WP_274332757.1 M20/M25/M40 family metallo-hydrolase -
PUP51_RS11865 (PUP51_11865) 2603833..2604228 + 396 WP_274332759.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10743.39 Da        Isoelectric Point: 10.0959

>T272831 WP_062822913.1 NZ_CP118144:c2599244-2598951 [Pseudomonas chlororaphis]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10223.78 Da        Isoelectric Point: 8.0096

>AT272831 WP_009043099.1 NZ_CP118144:c2598949-2598659 [Pseudomonas chlororaphis]
MSDTLLPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A285IMN7

References