Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 780967..781661 Replicon chromosome
Accession NZ_CP118144
Organism Pseudomonas chlororaphis strain ATCC 174181

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUP51_RS03515 Protein ID WP_062823884.1
Coordinates 780967..781263 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP51_RS03520 Protein ID WP_062823883.1
Coordinates 781260..781661 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP51_RS03480 (PUP51_03480) 776601..777146 - 546 WP_097134266.1 hypothetical protein -
PUP51_RS03485 (PUP51_03485) 777143..777397 - 255 WP_007926835.1 acyl carrier protein -
PUP51_RS03490 (PUP51_03490) 777407..777667 - 261 WP_007926834.1 phosphopantetheine-binding protein -
PUP51_RS03495 (PUP51_03495) 777642..778457 - 816 WP_062823887.1 lysophospholipid acyltransferase family protein -
PUP51_RS03500 (PUP51_03500) 778433..779164 - 732 WP_274331460.1 beta-ketoacyl synthase chain length factor -
PUP51_RS03505 (PUP51_03505) 779499..780269 + 771 WP_009041850.1 ParA family protein -
PUP51_RS03510 (PUP51_03510) 780308..780742 - 435 WP_062823885.1 thioredoxin TrxC -
PUP51_RS03515 (PUP51_03515) 780967..781263 + 297 WP_062823884.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP51_RS03520 (PUP51_03520) 781260..781661 + 402 WP_062823883.1 transcriptional regulator Antitoxin
PUP51_RS03525 (PUP51_03525) 781666..783129 - 1464 WP_274331465.1 YdiU family protein -
PUP51_RS03530 (PUP51_03530) 783178..786528 - 3351 WP_123573332.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Antitoxin HigA

(15-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11625.59 Da        Isoelectric Point: 10.7938

>T272828 WP_062823884.1 NZ_CP118144:780967-781263 [Pseudomonas chlororaphis]
MRVITAKRIWDAKEKWPQSAKALDDWYRALKRNRLADFAAMKAMFPAVDKVGPLHVFDIGGNKIRLIALVRYTTQKLYIR
HVLDHREYDRGKWKEDRG

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15183.39 Da        Isoelectric Point: 4.5530

>AT272828 WP_062823883.1 NZ_CP118144:781260-781661 [Pseudomonas chlororaphis]
MSALIEQVAEHWQFVAPLLRKPKTEADYDRLVQALDELLDLTGEDEAHPLNSLVDIIGDWIEAYDLEHRPMPVASGIDVL
RYMMREHGLTQSDLPGVGAQSVVSEILSGKRQLNLRQIRWLAERFKVSMETFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References