Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2598920..2599505 Replicon chromosome
Accession NZ_CP118143
Organism Pseudomonas chlororaphis strain ATCC 174182

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP62_RS11840 Protein ID WP_062822913.1
Coordinates 2599212..2599505 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A285IMN7
Locus tag PUP62_RS11835 Protein ID WP_009043099.1
Coordinates 2598920..2599210 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP62_RS11825 (PUP62_11825) 2596435..2597817 + 1383 WP_274332749.1 efflux transporter outer membrane subunit -
PUP62_RS11830 (PUP62_11830) 2597936..2598523 + 588 WP_274332750.1 hypothetical protein -
PUP62_RS11835 (PUP62_11835) 2598920..2599210 - 291 WP_009043099.1 putative addiction module antidote protein Antitoxin
PUP62_RS11840 (PUP62_11840) 2599212..2599505 - 294 WP_062822913.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP62_RS11845 (PUP62_11845) 2599741..2601135 - 1395 WP_123361693.1 VOC family protein -
PUP62_RS11850 (PUP62_11850) 2601400..2602524 + 1125 WP_274332755.1 diguanylate cyclase -
PUP62_RS11855 (PUP62_11855) 2602618..2603862 + 1245 WP_274332757.1 M20/M25/M40 family metallo-hydrolase -
PUP62_RS11860 (PUP62_11860) 2604094..2604489 + 396 WP_274332759.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10743.39 Da        Isoelectric Point: 10.0959

>T272823 WP_062822913.1 NZ_CP118143:c2599505-2599212 [Pseudomonas chlororaphis]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNMGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10223.78 Da        Isoelectric Point: 8.0096

>AT272823 WP_009043099.1 NZ_CP118143:c2599210-2598920 [Pseudomonas chlororaphis]
MSDTLLPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A285IMN7

References