Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1221634..1222172 Replicon chromosome
Accession NZ_CP118143
Organism Pseudomonas chlororaphis strain ATCC 174182

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUP62_RS05375 Protein ID WP_123362588.1
Coordinates 1221894..1222172 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP62_RS05370 Protein ID WP_274331764.1
Coordinates 1221634..1221897 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP62_RS05355 (PUP62_05355) 1217625..1219898 - 2274 WP_274331761.1 TonB-dependent siderophore receptor -
PUP62_RS05360 (PUP62_05360) 1220104..1220784 + 681 WP_009042146.1 Fe2+-dependent dioxygenase -
PUP62_RS05365 (PUP62_05365) 1220788..1221573 + 786 WP_274331763.1 tetratricopeptide repeat protein -
PUP62_RS05370 (PUP62_05370) 1221634..1221897 + 264 WP_274331764.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP62_RS05375 (PUP62_05375) 1221894..1222172 + 279 WP_123362588.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP62_RS05380 (PUP62_05380) 1222247..1223410 - 1164 WP_007923836.1 type III PLP-dependent enzyme -
PUP62_RS05385 (PUP62_05385) 1224111..1225268 - 1158 WP_274331765.1 ABC transporter ATP-binding protein -
PUP62_RS05390 (PUP62_05390) 1225265..1225918 - 654 WP_007923833.1 ABC transporter permease -
PUP62_RS05395 (PUP62_05395) 1225933..1226826 - 894 WP_274331766.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10874.52 Da        Isoelectric Point: 8.5619

>T272821 WP_123362588.1 NZ_CP118143:1221894-1222172 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVHSLTQAPDTLLINPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9796.22 Da        Isoelectric Point: 5.6088

>AT272821 WP_274331764.1 NZ_CP118143:1221634-1221897 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDVGRVIDHQAVQAWAESLMND
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References