Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 780791..781485 Replicon chromosome
Accession NZ_CP118143
Organism Pseudomonas chlororaphis strain ATCC 174182

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUP62_RS03515 Protein ID WP_062823884.1
Coordinates 780791..781087 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP62_RS03520 Protein ID WP_062823883.1
Coordinates 781084..781485 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP62_RS03480 (PUP62_03480) 776425..776970 - 546 WP_097134266.1 hypothetical protein -
PUP62_RS03485 (PUP62_03485) 776967..777221 - 255 WP_007926835.1 acyl carrier protein -
PUP62_RS03490 (PUP62_03490) 777231..777491 - 261 WP_007926834.1 phosphopantetheine-binding protein -
PUP62_RS03495 (PUP62_03495) 777466..778281 - 816 WP_062823887.1 lysophospholipid acyltransferase family protein -
PUP62_RS03500 (PUP62_03500) 778257..778988 - 732 WP_274331460.1 beta-ketoacyl synthase chain length factor -
PUP62_RS03505 (PUP62_03505) 779323..780093 + 771 WP_009041850.1 ParA family protein -
PUP62_RS03510 (PUP62_03510) 780132..780566 - 435 WP_062823885.1 thioredoxin TrxC -
PUP62_RS03515 (PUP62_03515) 780791..781087 + 297 WP_062823884.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP62_RS03520 (PUP62_03520) 781084..781485 + 402 WP_062823883.1 transcriptional regulator Antitoxin
PUP62_RS03525 (PUP62_03525) 781490..782953 - 1464 WP_274331465.1 YdiU family protein -
PUP62_RS03530 (PUP62_03530) 783002..786352 - 3351 WP_123573332.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Antitoxin HigA

(15-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11625.59 Da        Isoelectric Point: 10.7938

>T272820 WP_062823884.1 NZ_CP118143:780791-781087 [Pseudomonas chlororaphis]
MRVITAKRIWDAKEKWPQSAKALDDWYRALKRNRLADFAAMKAMFPAVDKVGPLHVFDIGGNKIRLIALVRYTTQKLYIR
HVLDHREYDRGKWKEDRG

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15183.39 Da        Isoelectric Point: 4.5530

>AT272820 WP_062823883.1 NZ_CP118143:781084-781485 [Pseudomonas chlororaphis]
MSALIEQVAEHWQFVAPLLRKPKTEADYDRLVQALDELLDLTGEDEAHPLNSLVDIIGDWIEAYDLEHRPMPVASGIDVL
RYMMREHGLTQSDLPGVGAQSVVSEILSGKRQLNLRQIRWLAERFKVSMETFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References