Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 559537..560207 Replicon chromosome
Accession NZ_CP118143
Organism Pseudomonas chlororaphis strain ATCC 174182

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP62_RS02490 Protein ID WP_062824000.1
Coordinates 559537..559965 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N8BIH3
Locus tag PUP62_RS02495 Protein ID WP_062823999.1
Coordinates 559962..560207 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP62_RS02475 (PUP62_02475) 554659..556917 + 2259 WP_274331319.1 TonB-dependent receptor -
PUP62_RS02480 (PUP62_02480) 556964..558289 + 1326 WP_274331320.1 LLM class flavin-dependent oxidoreductase -
PUP62_RS02485 (PUP62_02485) 558374..559411 + 1038 WP_274331322.1 L-glyceraldehyde 3-phosphate reductase -
PUP62_RS02490 (PUP62_02490) 559537..559965 - 429 WP_062824000.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP62_RS02495 (PUP62_02495) 559962..560207 - 246 WP_062823999.1 hypothetical protein Antitoxin
PUP62_RS02500 (PUP62_02500) 560335..561174 - 840 WP_274301720.1 taurine dioxygenase -
PUP62_RS02505 (PUP62_02505) 561370..562209 - 840 WP_085533374.1 taurine ABC transporter permease TauC -
PUP62_RS02510 (PUP62_02510) 562206..563000 - 795 WP_085533376.1 taurine ABC transporter ATP-binding subunit -
PUP62_RS02515 (PUP62_02515) 563095..564072 - 978 WP_274331324.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15811.42 Da        Isoelectric Point: 5.4927

>T272819 WP_062824000.1 NZ_CP118143:c559965-559537 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQMLHASALAMFEEDFIDRIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9129.35 Da        Isoelectric Point: 7.3226

>AT272819 WP_062823999.1 NZ_CP118143:c560207-559962 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALNRTTDSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8BIH3

References