272813

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4942404..4942989 Replicon chromosome
Accession NZ_CP118142
Organism Pseudomonas chlororaphis strain ATCC 17809

Toxin (Protein)


Gene name PumA Uniprot ID A0A3G7C0N8
Locus tag PUP81_RS22370 Protein ID WP_025804099.1
Coordinates 4942404..4942697 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A3G7CJP2
Locus tag PUP81_RS22375 Protein ID WP_025804100.1
Coordinates 4942699..4942989 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP81_RS22350 (PUP81_22350) 4937438..4937836 - 399 WP_016702749.1 carboxymuconolactone decarboxylase family protein -
PUP81_RS22355 (PUP81_22355) 4938049..4939293 - 1245 WP_124323954.1 M20/M25/M40 family metallo-hydrolase -
PUP81_RS22360 (PUP81_22360) 4939387..4940511 - 1125 WP_124323953.1 diguanylate cyclase -
PUP81_RS22365 (PUP81_22365) 4940774..4942168 + 1395 WP_124323952.1 VOC family protein -
PUP81_RS22370 (PUP81_22370) 4942404..4942697 + 294 WP_025804099.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP81_RS22375 (PUP81_22375) 4942699..4942989 + 291 WP_025804100.1 putative addiction module antidote protein Antitoxin
PUP81_RS22380 (PUP81_22380) 4943403..4943990 - 588 WP_063429489.1 hypothetical protein -
PUP81_RS22385 (PUP81_22385) 4944118..4945194 - 1077 WP_124323951.1 lipocalin-like domain-containing protein -
PUP81_RS22390 (PUP81_22390) 4945184..4947664 - 2481 WP_124325843.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(9-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10837.49 Da        Isoelectric Point: 10.7289

>T272813 WP_025804099.1 NZ_CP118142:4942404-4942697 [Pseudomonas chlororaphis]
MEYEILQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNRGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10249.81 Da        Isoelectric Point: 8.0096

>AT272813 WP_025804100.1 NZ_CP118142:4942699-4942989 [Pseudomonas chlororaphis]
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G7C0N8

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7CJP2

References