272811

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6265958..6266547 Replicon chromosome
Accession NZ_CP118141
Organism Pseudomonas chlororaphis strain ATCC 17814

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP70_RS28475 Protein ID WP_007924097.1
Coordinates 6266248..6266547 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP70_RS28470 Protein ID WP_009045810.1
Coordinates 6265958..6266251 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP70_RS28445 (PUP70_28445) 6261673..6262131 + 459 WP_053262808.1 GNAT family N-acetyltransferase -
PUP70_RS28450 (PUP70_28450) 6262385..6263041 + 657 WP_007924093.1 DedA family protein -
PUP70_RS28455 (PUP70_28455) 6263047..6263856 + 810 WP_053262809.1 zinc-dependent peptidase -
PUP70_RS28460 (PUP70_28460) 6264121..6264648 + 528 WP_003228599.1 inorganic diphosphatase -
PUP70_RS28465 (PUP70_28465) 6265456..6265842 + 387 WP_053262810.1 hypothetical protein -
PUP70_RS28470 (PUP70_28470) 6265958..6266251 - 294 WP_009045810.1 putative addiction module antidote protein Antitoxin
PUP70_RS28475 (PUP70_28475) 6266248..6266547 - 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP70_RS28480 (PUP70_28480) 6266719..6267168 + 450 WP_053262811.1 DUF3828 domain-containing protein -
PUP70_RS28485 (PUP70_28485) 6267193..6268203 - 1011 WP_173613368.1 NAD(P)-dependent alcohol dehydrogenase -
PUP70_RS28490 (PUP70_28490) 6268261..6268560 - 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP70_RS28495 (PUP70_28495) 6268627..6269715 - 1089 WP_053262813.1 copper-containing nitrite reductase -
PUP70_RS28500 (PUP70_28500) 6269942..6270184 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP70_RS28505 (PUP70_28505) 6270181..6271068 + 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T272811 WP_007924097.1 NZ_CP118141:c6266547-6266248 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT272811 WP_009045810.1 NZ_CP118141:c6266251-6265958 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References