Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 6033694..6034322 Replicon chromosome
Accession NZ_CP118140
Organism Pseudomonas chlororaphis strain ATCC 336632

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP57_RS27150 Protein ID WP_038576104.1
Coordinates 6033694..6034092 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PUP57_RS27155 Protein ID WP_081359896.1
Coordinates 6034092..6034322 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP57_RS27120 (PUP57_27120) 6028932..6029207 + 276 WP_038576112.1 hypothetical protein -
PUP57_RS27125 (PUP57_27125) 6029414..6029590 + 177 WP_164486677.1 hypothetical protein -
PUP57_RS27130 (PUP57_27130) 6029795..6030292 + 498 WP_081363157.1 PAAR domain-containing protein -
PUP57_RS27135 (PUP57_27135) 6030296..6031030 + 735 WP_081359899.1 alpha/beta hydrolase -
PUP57_RS27140 (PUP57_27140) 6031027..6031551 + 525 WP_081359898.1 hypothetical protein -
PUP57_RS27145 (PUP57_27145) 6031687..6033636 + 1950 WP_081359897.1 alkaline phosphatase D family protein -
PUP57_RS27150 (PUP57_27150) 6033694..6034092 - 399 WP_038576104.1 tRNA(fMet)-specific endonuclease VapC Toxin
PUP57_RS27155 (PUP57_27155) 6034092..6034322 - 231 WP_081359896.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PUP57_RS27160 (PUP57_27160) 6034600..6035577 + 978 WP_081359895.1 type I-F CRISPR-associated endonuclease Cas1f -
PUP57_RS27165 (PUP57_27165) 6035574..6038990 + 3417 WP_081359894.1 type I-F CRISPR-associated helicase Cas3f -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14886.17 Da        Isoelectric Point: 7.2433

>T272805 WP_038576104.1 NZ_CP118140:c6034092-6033694 [Pseudomonas chlororaphis]
MLKYMLDTNICIFTIKNKPERVREAFNRQHGRLCISSVTLMELIYGAEKSAAPERNLSVIEGFVARLEVLAYDYEAAIHS
GQLRAELARAGTPIGPYDQLIAGHARSQGLVLVTNNVREFERVPGLRIEDWL

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8514.44 Da        Isoelectric Point: 4.2821

>AT272805 WP_081359896.1 NZ_CP118140:c6034322-6034092 [Pseudomonas chlororaphis]
MEQGSVFKSNRSQAIRMPKAVALPDDVTRVDIVAVGRTRIITPAGEAWDSWFDGESVSADFMNERDQPAEQEREAF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References