Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4691759..4692278 Replicon chromosome
Accession NZ_CP118140
Organism Pseudomonas chlororaphis strain ATCC 336632

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUP57_RS21040 Protein ID WP_081360541.1
Coordinates 4691759..4692040 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1H3UB71
Locus tag PUP57_RS21045 Protein ID WP_009044432.1
Coordinates 4692030..4692278 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP57_RS21020 (PUP57_21020) 4687381..4687653 + 273 WP_081360544.1 hypothetical protein -
PUP57_RS21025 (PUP57_21025) 4688286..4689077 + 792 WP_081360543.1 methyltransferase domain-containing protein -
PUP57_RS21030 (PUP57_21030) 4689393..4689875 + 483 WP_009049637.1 acyl-CoA thioesterase -
PUP57_RS21035 (PUP57_21035) 4689932..4691581 + 1650 WP_081360542.1 FMN-binding glutamate synthase family protein -
PUP57_RS21040 (PUP57_21040) 4691759..4692040 - 282 WP_081360541.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP57_RS21045 (PUP57_21045) 4692030..4692278 - 249 WP_009044432.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP57_RS21050 (PUP57_21050) 4692375..4693163 - 789 WP_081360540.1 helix-turn-helix transcriptional regulator -
PUP57_RS21055 (PUP57_21055) 4693248..4694246 + 999 WP_081360539.1 bile acid:sodium symporter family protein -
PUP57_RS21060 (PUP57_21060) 4694460..4696223 + 1764 WP_081360538.1 hypothetical protein -
PUP57_RS21065 (PUP57_21065) 4696296..4696757 + 462 WP_009049642.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10821.62 Da        Isoelectric Point: 10.5816

>T272804 WP_081360541.1 NZ_CP118140:c4692040-4691759 [Pseudomonas chlororaphis]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQASKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8997.37 Da        Isoelectric Point: 4.4142

>AT272804 WP_009044432.1 NZ_CP118140:c4692278-4692030 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTIKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1H3UB71

References