Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 561152..561822 Replicon chromosome
Accession NZ_CP118140
Organism Pseudomonas chlororaphis strain ATCC 336632

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP57_RS02495 Protein ID WP_081362979.1
Coordinates 561152..561580 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag PUP57_RS02500 Protein ID WP_009046453.1
Coordinates 561577..561822 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP57_RS02480 (PUP57_02480) 556271..558529 + 2259 WP_081362982.1 TonB-dependent receptor -
PUP57_RS02485 (PUP57_02485) 558576..559901 + 1326 WP_081362981.1 LLM class flavin-dependent oxidoreductase -
PUP57_RS02490 (PUP57_02490) 559986..561023 + 1038 WP_081362980.1 L-glyceraldehyde 3-phosphate reductase -
PUP57_RS02495 (PUP57_02495) 561152..561580 - 429 WP_081362979.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP57_RS02500 (PUP57_02500) 561577..561822 - 246 WP_009046453.1 plasmid stabilization protein Antitoxin
PUP57_RS02505 (PUP57_02505) 561962..562801 - 840 WP_081362978.1 taurine dioxygenase -
PUP57_RS02510 (PUP57_02510) 563029..563868 - 840 WP_081362977.1 taurine ABC transporter permease TauC -
PUP57_RS02515 (PUP57_02515) 563865..564659 - 795 WP_081362976.1 taurine ABC transporter ATP-binding subunit -
PUP57_RS02520 (PUP57_02520) 564755..565732 - 978 WP_081362975.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15853.36 Da        Isoelectric Point: 5.4927

>T272801 WP_081362979.1 NZ_CP118140:c561580-561152 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASAVAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT272801 WP_009046453.1 NZ_CP118140:c561822-561577 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References