Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6663153..6663742 Replicon chromosome
Accession NZ_CP118139
Organism Pseudomonas chlororaphis strain DSM 295781

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP68_RS30015 Protein ID WP_210476686.1
Coordinates 6663443..6663742 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP68_RS30010 Protein ID WP_053281098.1
Coordinates 6663153..6663446 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP68_RS29985 (PUP68_29985) 6658788..6659516 + 729 WP_053281093.1 ABC transporter permease -
PUP68_RS29990 (PUP68_29990) 6659513..6660223 + 711 WP_053281094.1 ABC transporter permease -
PUP68_RS29995 (PUP68_29995) 6660240..6661004 + 765 WP_053281095.1 ATP-binding cassette domain-containing protein -
PUP68_RS30000 (PUP68_30000) 6661391..6661783 + 393 WP_053281096.1 DUF3077 domain-containing protein -
PUP68_RS30005 (PUP68_30005) 6661984..6663147 + 1164 WP_053281097.1 GGDEF domain-containing protein -
PUP68_RS30010 (PUP68_30010) 6663153..6663446 - 294 WP_053281098.1 putative addiction module antidote protein Antitoxin
PUP68_RS30015 (PUP68_30015) 6663443..6663742 - 300 WP_210476686.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP68_RS30020 (PUP68_30020) 6663915..6664364 + 450 WP_053281099.1 DUF3828 domain-containing protein -
PUP68_RS30025 (PUP68_30025) 6664389..6665399 - 1011 WP_172833187.1 NAD(P)-dependent alcohol dehydrogenase -
PUP68_RS30030 (PUP68_30030) 6665456..6665755 - 300 WP_053281101.1 helix-turn-helix transcriptional regulator -
PUP68_RS30035 (PUP68_30035) 6665822..6666910 - 1089 WP_053281102.1 copper-containing nitrite reductase -
PUP68_RS30040 (PUP68_30040) 6667138..6667380 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP68_RS30045 (PUP68_30045) 6667377..6668264 + 888 WP_053281103.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11191.90 Da        Isoelectric Point: 10.6086

>T272799 WP_210476686.1 NZ_CP118139:c6663742-6663443 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQGRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10584.16 Da        Isoelectric Point: 6.4627

>AT272799 WP_053281098.1 NZ_CP118139:c6663446-6663153 [Pseudomonas chlororaphis]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHVRP

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References