Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2661867..2662452 Replicon chromosome
Accession NZ_CP118139
Organism Pseudomonas chlororaphis strain DSM 295781

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP68_RS12315 Protein ID WP_210689320.1
Coordinates 2662159..2662452 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP68_RS12310 Protein ID WP_053278358.1
Coordinates 2661867..2662157 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP68_RS12295 (PUP68_12295) 2657192..2659672 + 2481 WP_274320650.1 FtsX-like permease family protein -
PUP68_RS12300 (PUP68_12300) 2659662..2660738 + 1077 WP_053278356.1 lipocalin-like domain-containing protein -
PUP68_RS12305 (PUP68_12305) 2660866..2661453 + 588 WP_053278357.1 hypothetical protein -
PUP68_RS12310 (PUP68_12310) 2661867..2662157 - 291 WP_053278358.1 putative addiction module antidote protein Antitoxin
PUP68_RS12315 (PUP68_12315) 2662159..2662452 - 294 WP_210689320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP68_RS12320 (PUP68_12320) 2662688..2664082 - 1395 WP_274320649.1 VOC family protein -
PUP68_RS12325 (PUP68_12325) 2664345..2665469 + 1125 WP_053278361.1 diguanylate cyclase -
PUP68_RS12330 (PUP68_12330) 2665563..2666807 + 1245 WP_274320648.1 M20/M25/M40 family metallo-hydrolase -
PUP68_RS12335 (PUP68_12335) 2667015..2667413 + 399 WP_053278363.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(41-83)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10768.38 Da        Isoelectric Point: 10.4234

>T272797 WP_210689320.1 NZ_CP118139:c2662452-2662159 [Pseudomonas chlororaphis]
MDYEILQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10219.79 Da        Isoelectric Point: 8.0096

>AT272797 WP_053278358.1 NZ_CP118139:c2662157-2661867 [Pseudomonas chlororaphis]
MSDTLVPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References