Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 7038471..7039056 Replicon chromosome
Accession NZ_CP118138
Organism Pseudomonas chlororaphis strain DSM 295782

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP77_RS31840 Protein ID WP_210689320.1
Coordinates 7038471..7038764 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP77_RS31845 Protein ID WP_053278358.1
Coordinates 7038766..7039056 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP77_RS31820 (PUP77_31820) 7033510..7033908 - 399 WP_053278363.1 carboxymuconolactone decarboxylase family protein -
PUP77_RS31825 (PUP77_31825) 7034116..7035360 - 1245 WP_274320648.1 M20/M25/M40 family metallo-hydrolase -
PUP77_RS31830 (PUP77_31830) 7035454..7036578 - 1125 WP_053278361.1 diguanylate cyclase -
PUP77_RS31835 (PUP77_31835) 7036841..7038235 + 1395 WP_274320649.1 VOC family protein -
PUP77_RS31840 (PUP77_31840) 7038471..7038764 + 294 WP_210689320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP77_RS31845 (PUP77_31845) 7038766..7039056 + 291 WP_053278358.1 putative addiction module antidote protein Antitoxin
PUP77_RS31850 (PUP77_31850) 7039470..7040057 - 588 WP_053278357.1 hypothetical protein -
PUP77_RS31855 (PUP77_31855) 7040185..7041261 - 1077 WP_053278356.1 lipocalin-like domain-containing protein -
PUP77_RS31860 (PUP77_31860) 7041251..7043731 - 2481 WP_274320650.1 FtsX-like permease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(41-83)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10768.38 Da        Isoelectric Point: 10.4234

>T272792 WP_210689320.1 NZ_CP118138:7038471-7038764 [Pseudomonas chlororaphis]
MDYEILQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10219.79 Da        Isoelectric Point: 8.0096

>AT272792 WP_053278358.1 NZ_CP118138:7038766-7039056 [Pseudomonas chlororaphis]
MSDTLVPFDIAALLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References