Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 3200246..3200835 Replicon chromosome
Accession NZ_CP118138
Organism Pseudomonas chlororaphis strain DSM 295782

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP77_RS14845 Protein ID WP_210476686.1
Coordinates 3200246..3200545 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP77_RS14850 Protein ID WP_053281098.1
Coordinates 3200542..3200835 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP77_RS14815 (PUP77_14815) 3195724..3196611 - 888 WP_053281103.1 (2E,6E)-farnesyl diphosphate synthase -
PUP77_RS14820 (PUP77_14820) 3196608..3196850 - 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP77_RS14825 (PUP77_14825) 3197078..3198166 + 1089 WP_053281102.1 copper-containing nitrite reductase -
PUP77_RS14830 (PUP77_14830) 3198233..3198532 + 300 WP_053281101.1 helix-turn-helix transcriptional regulator -
PUP77_RS14835 (PUP77_14835) 3198589..3199599 + 1011 WP_172833187.1 NAD(P)-dependent alcohol dehydrogenase -
PUP77_RS14840 (PUP77_14840) 3199624..3200073 - 450 WP_053281099.1 DUF3828 domain-containing protein -
PUP77_RS14845 (PUP77_14845) 3200246..3200545 + 300 WP_210476686.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP77_RS14850 (PUP77_14850) 3200542..3200835 + 294 WP_053281098.1 putative addiction module antidote protein Antitoxin
PUP77_RS14855 (PUP77_14855) 3200841..3202004 - 1164 WP_053281097.1 GGDEF domain-containing protein -
PUP77_RS14860 (PUP77_14860) 3202205..3202597 - 393 WP_053281096.1 DUF3077 domain-containing protein -
PUP77_RS14865 (PUP77_14865) 3202984..3203748 - 765 WP_053281095.1 ATP-binding cassette domain-containing protein -
PUP77_RS14870 (PUP77_14870) 3203765..3204475 - 711 WP_053281094.1 ABC transporter permease -
PUP77_RS14875 (PUP77_14875) 3204472..3205200 - 729 WP_053281093.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11191.90 Da        Isoelectric Point: 10.6086

>T272790 WP_210476686.1 NZ_CP118138:3200246-3200545 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQGRDIELAKQLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10584.16 Da        Isoelectric Point: 6.4627

>AT272790 WP_053281098.1 NZ_CP118138:3200542-3200835 [Pseudomonas chlororaphis]
MNEPLFDYDPATSLRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHVRP

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References