Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 545294..545964 Replicon chromosome
Accession NZ_CP118137
Organism Pseudomonas chlororaphis strain NCCB 47033

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP65_RS02435 Protein ID WP_124323278.1
Coordinates 545294..545722 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag PUP65_RS02440 Protein ID WP_009046453.1
Coordinates 545719..545964 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP65_RS02405 (PUP65_02405) 540493..540981 - 489 WP_124323274.1 DoxX family membrane protein -
PUP65_RS02410 (PUP65_02410) 541038..541778 - 741 WP_124323275.1 SDR family oxidoreductase -
PUP65_RS02415 (PUP65_02415) 541908..542798 + 891 WP_124323276.1 LysR family transcriptional regulator -
PUP65_RS02420 (PUP65_02420) 542923..543105 + 183 WP_009041685.1 type II toxin-antitoxin system HicA family toxin -
PUP65_RS02425 (PUP65_02425) 543135..543536 + 402 WP_025808441.1 type II toxin-antitoxin system HicB family antitoxin -
PUP65_RS02430 (PUP65_02430) 544127..545164 + 1038 WP_124323277.1 L-glyceraldehyde 3-phosphate reductase -
PUP65_RS02435 (PUP65_02435) 545294..545722 - 429 WP_124323278.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP65_RS02440 (PUP65_02440) 545719..545964 - 246 WP_009046453.1 plasmid stabilization protein Antitoxin
PUP65_RS02445 (PUP65_02445) 546104..546943 - 840 WP_124323279.1 taurine dioxygenase -
PUP65_RS02450 (PUP65_02450) 547181..548020 - 840 WP_124323280.1 taurine ABC transporter permease TauC -
PUP65_RS02455 (PUP65_02455) 548017..548811 - 795 WP_023970012.1 taurine ABC transporter ATP-binding subunit -
PUP65_RS02460 (PUP65_02460) 548922..549899 - 978 WP_124323281.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15862.37 Da        Isoelectric Point: 5.4577

>T272782 WP_124323278.1 NZ_CP118137:c545722-545294 [Pseudomonas chlororaphis]
MIVLDTNVLSELMHPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASALAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEI

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT272782 WP_009046453.1 NZ_CP118137:c545964-545719 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References