Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 433022..433538 Replicon chromosome
Accession NZ_CP118136
Organism Pseudomonas chlororaphis strain NCCB 60038

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag PUP52_RS01915 Protein ID WP_009041601.1
Coordinates 433257..433538 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag PUP52_RS01910 Protein ID WP_009046356.1
Coordinates 433022..433267 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP52_RS01885 (PUP52_01885) 428790..429785 + 996 WP_041985268.1 aspartyl beta-hydroxylase -
PUP52_RS01890 (PUP52_01890) 429751..430509 - 759 WP_009046352.1 slipin family protein -
PUP52_RS01895 (PUP52_01895) 430511..431896 - 1386 WP_009046353.1 nodulation protein NfeD -
PUP52_RS01900 (PUP52_01900) 432120..432581 + 462 WP_016705004.1 YbaK/EbsC family protein -
PUP52_RS01905 (PUP52_01905) 432712..432957 + 246 WP_009046355.1 DUF2789 domain-containing protein -
PUP52_RS01910 (PUP52_01910) 433022..433267 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP52_RS01915 (PUP52_01915) 433257..433538 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP52_RS01920 (PUP52_01920) 433671..434099 + 429 WP_009046358.1 MarR family transcriptional regulator -
PUP52_RS01925 (PUP52_01925) 434096..436180 + 2085 WP_041985273.1 FUSC family protein -
PUP52_RS01930 (PUP52_01930) 436177..436386 + 210 WP_041985274.1 DUF1656 domain-containing protein -
PUP52_RS01935 (PUP52_01935) 436383..437276 + 894 WP_041985277.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T272774 WP_009041601.1 NZ_CP118136:433257-433538 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT272774 WP_009046356.1 NZ_CP118136:433022-433267 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References