Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 5051929..5052448 Replicon chromosome
Accession NZ_CP118135
Organism Pseudomonas chlororaphis strain NCCB 820532

Toxin (Protein)


Gene name relE Uniprot ID A0A1H3UB31
Locus tag PUP76_RS23205 Protein ID WP_007930524.1
Coordinates 5052167..5052448 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1H3UB71
Locus tag PUP76_RS23200 Protein ID WP_009044432.1
Coordinates 5051929..5052177 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP76_RS23180 (PUP76_23180) 5047337..5047798 - 462 WP_274300393.1 YccF domain-containing protein -
PUP76_RS23185 (PUP76_23185) 5047871..5049637 - 1767 WP_274300394.1 hypothetical protein -
PUP76_RS23190 (PUP76_23190) 5049961..5050959 - 999 WP_114760888.1 bile acid:sodium symporter family protein -
PUP76_RS23195 (PUP76_23195) 5051044..5051832 + 789 WP_085534323.1 helix-turn-helix transcriptional regulator -
PUP76_RS23200 (PUP76_23200) 5051929..5052177 + 249 WP_009044432.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP76_RS23205 (PUP76_23205) 5052167..5052448 + 282 WP_007930524.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP76_RS23210 (PUP76_23210) 5052640..5054289 - 1650 WP_274300395.1 FMN-binding glutamate synthase family protein -
PUP76_RS23215 (PUP76_23215) 5054342..5054824 - 483 WP_009044429.1 acyl-CoA thioesterase -
PUP76_RS23220 (PUP76_23220) 5055963..5056235 - 273 WP_007927368.1 hypothetical protein -
PUP76_RS23225 (PUP76_23225) 5056546..5057127 + 582 WP_253364919.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10890.73 Da        Isoelectric Point: 10.6993

>T272771 WP_007930524.1 NZ_CP118135:5052167-5052448 [Pseudomonas chlororaphis]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8997.37 Da        Isoelectric Point: 4.4142

>AT272771 WP_009044432.1 NZ_CP118135:5051929-5052177 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTIKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H3UB31

Antitoxin

Source ID Structure
AlphaFold DB A0A1H3UB71

References