Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2090872..2091388 Replicon chromosome
Accession NZ_CP118135
Organism Pseudomonas chlororaphis strain NCCB 820532

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag PUP76_RS09595 Protein ID WP_009041601.1
Coordinates 2090872..2091153 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A285F0M2
Locus tag PUP76_RS09600 Protein ID WP_062824057.1
Coordinates 2091143..2091388 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP76_RS09575 (PUP76_09575) 2087132..2088028 - 897 WP_274301765.1 HlyD family secretion protein -
PUP76_RS09580 (PUP76_09580) 2088025..2088234 - 210 WP_007932080.1 DUF1656 domain-containing protein -
PUP76_RS09585 (PUP76_09585) 2088231..2090315 - 2085 WP_087092318.1 FUSC family protein -
PUP76_RS09590 (PUP76_09590) 2090312..2090740 - 429 WP_085533251.1 MarR family transcriptional regulator -
PUP76_RS09595 (PUP76_09595) 2090872..2091153 - 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP76_RS09600 (PUP76_09600) 2091143..2091388 - 246 WP_062824057.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP76_RS09605 (PUP76_09605) 2091451..2091696 - 246 WP_009041599.1 DUF2789 domain-containing protein -
PUP76_RS09610 (PUP76_09610) 2091834..2092295 - 462 WP_062824058.1 YbaK/EbsC family protein -
PUP76_RS09615 (PUP76_09615) 2092519..2093904 + 1386 WP_274301766.1 nodulation protein NfeD -
PUP76_RS09620 (PUP76_09620) 2093906..2094664 + 759 WP_097134106.1 slipin family protein -
PUP76_RS09625 (PUP76_09625) 2094630..2095625 - 996 WP_274301767.1 sulfotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T272769 WP_009041601.1 NZ_CP118135:c2091153-2090872 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8822.17 Da        Isoelectric Point: 5.0216

>AT272769 WP_062824057.1 NZ_CP118135:c2091388-2091143 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLSGAHGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A285F0M2

References