Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1974054..1974724 Replicon chromosome
Accession NZ_CP118135
Organism Pseudomonas chlororaphis strain NCCB 820532

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP76_RS09065 Protein ID WP_123411912.1
Coordinates 1974296..1974724 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N8BIH3
Locus tag PUP76_RS09060 Protein ID WP_062823999.1
Coordinates 1974054..1974299 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP76_RS09040 (PUP76_09040) 1970300..1971277 + 978 WP_009041696.1 taurine ABC transporter substrate-binding protein -
PUP76_RS09045 (PUP76_09045) 1971372..1972166 + 795 WP_085533376.1 taurine ABC transporter ATP-binding subunit -
PUP76_RS09050 (PUP76_09050) 1972163..1973002 + 840 WP_009041694.1 taurine ABC transporter permease TauC -
PUP76_RS09055 (PUP76_09055) 1973087..1973926 + 840 WP_274301720.1 taurine dioxygenase -
PUP76_RS09060 (PUP76_09060) 1974054..1974299 + 246 WP_062823999.1 hypothetical protein Antitoxin
PUP76_RS09065 (PUP76_09065) 1974296..1974724 + 429 WP_123411912.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP76_RS09070 (PUP76_09070) 1974850..1975887 - 1038 WP_053259262.1 L-glyceraldehyde 3-phosphate reductase -
PUP76_RS09075 (PUP76_09075) 1975972..1977297 - 1326 WP_009041689.1 LLM class flavin-dependent oxidoreductase -
PUP76_RS09080 (PUP76_09080) 1977344..1979602 - 2259 WP_274301721.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15853.46 Da        Isoelectric Point: 5.4985

>T272767 WP_123411912.1 NZ_CP118135:1974296-1974724 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGRRKQMLHASALAMFEEDFIERIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9129.35 Da        Isoelectric Point: 7.3226

>AT272767 WP_062823999.1 NZ_CP118135:1974054-1974299 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALNRTTDSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8BIH3

References