Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1292856..1293394 Replicon chromosome
Accession NZ_CP118135
Organism Pseudomonas chlororaphis strain NCCB 820532

Toxin (Protein)


Gene name relE Uniprot ID A0A285H8D2
Locus tag PUP76_RS06085 Protein ID WP_009042149.1
Coordinates 1292856..1293134 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP76_RS06090 Protein ID WP_009042148.1
Coordinates 1293131..1293394 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP76_RS06065 (PUP76_06065) 1288350..1289243 + 894 WP_274301533.1 glycine betaine ABC transporter substrate-binding protein -
PUP76_RS06070 (PUP76_06070) 1289258..1289911 + 654 WP_053259627.1 ABC transporter permease -
PUP76_RS06075 (PUP76_06075) 1289908..1291065 + 1158 WP_274301534.1 ABC transporter ATP-binding protein -
PUP76_RS06080 (PUP76_06080) 1291618..1292781 + 1164 WP_009042150.1 type III PLP-dependent enzyme -
PUP76_RS06085 (PUP76_06085) 1292856..1293134 - 279 WP_009042149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP76_RS06090 (PUP76_06090) 1293131..1293394 - 264 WP_009042148.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP76_RS06095 (PUP76_06095) 1293455..1294240 - 786 WP_274301535.1 tetratricopeptide repeat protein -
PUP76_RS06100 (PUP76_06100) 1294244..1294924 - 681 WP_085529819.1 Fe2+-dependent dioxygenase -
PUP76_RS06105 (PUP76_06105) 1295130..1297403 + 2274 WP_085529818.1 TonB-dependent siderophore receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10853.45 Da        Isoelectric Point: 8.5409

>T272765 WP_009042149.1 NZ_CP118135:c1293134-1292856 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9768.17 Da        Isoelectric Point: 5.6088

>AT272765 WP_009042148.1 NZ_CP118135:c1293394-1293131 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGRVIDHQAVQAWAESLMND
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285H8D2

Antitoxin

Source ID Structure

References