Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 4143850..4145067 | Replicon | chromosome |
| Accession | NZ_CP118134 | ||
| Organism | Pseudomonas synxantha strain ATCC 17413 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | PUP72_RS18590 | Protein ID | WP_046068824.1 |
| Coordinates | 4144495..4145067 (+) | Length | 191 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | PUP72_RS18585 | Protein ID | WP_046068823.1 |
| Coordinates | 4143850..4144407 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PUP72_RS18570 (PUP72_18570) | 4139506..4140246 | + | 741 | WP_274354949.1 | molecular chaperone | - |
| PUP72_RS18575 (PUP72_18575) | 4140332..4142842 | + | 2511 | WP_274354950.1 | fimbria/pilus outer membrane usher protein | - |
| PUP72_RS18580 (PUP72_18580) | 4142902..4143738 | + | 837 | WP_274354951.1 | HAD family acid phosphatase | - |
| PUP72_RS18585 (PUP72_18585) | 4143850..4144407 | + | 558 | WP_046068823.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| PUP72_RS18590 (PUP72_18590) | 4144495..4145067 | + | 573 | WP_046068824.1 | HD domain-containing protein | Toxin |
| PUP72_RS18595 (PUP72_18595) | 4145077..4145499 | - | 423 | WP_046068825.1 | RidA family protein | - |
| PUP72_RS18600 (PUP72_18600) | 4145511..4147094 | - | 1584 | WP_274354952.1 | FAD-dependent oxidoreductase | - |
| PUP72_RS18605 (PUP72_18605) | 4147107..4148030 | - | 924 | WP_274354953.1 | ABC transporter substrate-binding protein | - |
| PUP72_RS18610 (PUP72_18610) | 4148048..4148821 | - | 774 | WP_056846688.1 | amino acid ABC transporter ATP-binding protein | - |
| PUP72_RS18615 (PUP72_18615) | 4148814..4149785 | - | 972 | WP_274354954.1 | amino acid ABC transporter permease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 21287.39 Da Isoelectric Point: 4.9633
>T272763 WP_046068824.1 NZ_CP118134:4144495-4145067 [Pseudomonas synxantha]
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLLLAQSLDSPLKTEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLLLAQSLDSPLKTEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE
Download Length: 573 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20524.53 Da Isoelectric Point: 7.8770
>AT272763 WP_046068823.1 NZ_CP118134:4143850-4144407 [Pseudomonas synxantha]
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGIQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRALQFTSPLTDLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGIQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRALQFTSPLTDLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|