Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1330291..1330926 Replicon chromosome
Accession NZ_CP118108
Organism Paenibacillus urinalis strain 2022CK-00829

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PUW25_RS05900 Protein ID WP_047912142.1
Coordinates 1330576..1330926 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PUW25_RS05895 Protein ID WP_047912143.1
Coordinates 1330291..1330572 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW25_RS05880 (PUW25_05880) 1326536..1327099 + 564 WP_047912146.1 transcriptional regulator -
PUW25_RS05885 (PUW25_05885) 1327290..1328528 + 1239 WP_047912145.1 DUF4367 domain-containing protein -
PUW25_RS05890 (PUW25_05890) 1328867..1330063 + 1197 WP_047912144.1 alanine racemase -
PUW25_RS05895 (PUW25_05895) 1330291..1330572 + 282 WP_047912143.1 ribbon-helix-helix protein, CopG family Antitoxin
PUW25_RS05900 (PUW25_05900) 1330576..1330926 + 351 WP_047912142.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PUW25_RS05905 (PUW25_05905) 1331186..1333375 + 2190 WP_047912304.1 alpha-galactosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12779.76 Da        Isoelectric Point: 4.8384

>T272759 WP_047912142.1 NZ_CP118108:1330576-1330926 [Paenibacillus urinalis]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTCIVAAITAQIQKAKLPTHVEIDAELHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDDDTMKLVGEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10738.34 Da        Isoelectric Point: 7.2024

>AT272759 WP_047912143.1 NZ_CP118108:1330291-1330572 [Paenibacillus urinalis]
MTNVQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYLNERKKRYIRESMQRGYMEMAKINLTMASEAFHAED
DADSTLGRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References