Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2786317..2786952 Replicon chromosome
Accession NZ_CP118106
Organism Paenibacillus urinalis strain 2022CK-00833

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PUW24_RS13775 Protein ID WP_047912142.1
Coordinates 2786602..2786952 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PUW24_RS13770 Protein ID WP_047912143.1
Coordinates 2786317..2786598 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW24_RS13755 (PUW24_13755) 2782562..2783125 + 564 WP_047912146.1 transcriptional regulator -
PUW24_RS13760 (PUW24_13760) 2783316..2784554 + 1239 WP_047912145.1 DUF4367 domain-containing protein -
PUW24_RS13765 (PUW24_13765) 2784893..2786089 + 1197 WP_047912144.1 alanine racemase -
PUW24_RS13770 (PUW24_13770) 2786317..2786598 + 282 WP_047912143.1 ribbon-helix-helix protein, CopG family Antitoxin
PUW24_RS13775 (PUW24_13775) 2786602..2786952 + 351 WP_047912142.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PUW24_RS13780 (PUW24_13780) 2787212..2789401 + 2190 WP_047912304.1 alpha-galactosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12779.76 Da        Isoelectric Point: 4.8384

>T272758 WP_047912142.1 NZ_CP118106:2786602-2786952 [Paenibacillus urinalis]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTCIVAAITAQIQKAKLPTHVEIDAELHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDDDTMKLVGEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10738.34 Da        Isoelectric Point: 7.2024

>AT272758 WP_047912143.1 NZ_CP118106:2786317-2786598 [Paenibacillus urinalis]
MTNVQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYLNERKKRYIRESMQRGYMEMAKINLTMASEAFHAED
DADSTLGRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References