Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1458062..1458697 Replicon chromosome
Accession NZ_CP118101
Organism Paenibacillus urinalis strain 2022CK-00830

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PUW23_RS06370 Protein ID WP_047912142.1
Coordinates 1458347..1458697 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PUW23_RS06365 Protein ID WP_047912143.1
Coordinates 1458062..1458343 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW23_RS06350 (PUW23_06350) 1454311..1454874 + 564 WP_205053870.1 GbsR/MarR family transcriptional regulator -
PUW23_RS06355 (PUW23_06355) 1455061..1456299 + 1239 WP_205053869.1 outer membrane lipoprotein-sorting protein -
PUW23_RS06360 (PUW23_06360) 1456638..1457834 + 1197 WP_205053868.1 alanine racemase -
PUW23_RS06365 (PUW23_06365) 1458062..1458343 + 282 WP_047912143.1 ribbon-helix-helix protein, CopG family Antitoxin
PUW23_RS06370 (PUW23_06370) 1458347..1458697 + 351 WP_047912142.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PUW23_RS06375 (PUW23_06375) 1459299..1460591 + 1293 WP_274338793.1 group II intron reverse transcriptase/maturase -
PUW23_RS06380 (PUW23_06380) 1460891..1463080 + 2190 WP_205053864.1 alpha-galactosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12779.76 Da        Isoelectric Point: 4.8384

>T272757 WP_047912142.1 NZ_CP118101:1458347-1458697 [Paenibacillus urinalis]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTCIVAAITAQIQKAKLPTHVEIDAELHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDDDTMKLVGEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10738.34 Da        Isoelectric Point: 7.2024

>AT272757 WP_047912143.1 NZ_CP118101:1458062-1458343 [Paenibacillus urinalis]
MTNVQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYLNERKKRYIRESMQRGYMEMAKINLTMASEAFHAED
DADSTLGRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References