Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-DinJ
Location 1192473..1192998 Replicon chromosome
Accession NZ_CP118095
Organism Aerococcus christensenii strain VSI03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUW42_RS05665 Protein ID WP_274980588.1
Coordinates 1192720..1192998 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag PUW42_RS05660 Protein ID WP_274980587.1
Coordinates 1192473..1192733 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW42_RS05640 (PUW42_05640) 1188245..1189951 - 1707 WP_274980583.1 terminase large subunit -
PUW42_RS05645 (PUW42_05645) 1189956..1190429 - 474 WP_274980584.1 P27 family phage terminase small subunit -
PUW42_RS05650 (PUW42_05650) 1191382..1191561 + 180 WP_274980585.1 hypothetical protein -
PUW42_RS05655 (PUW42_05655) 1191826..1192263 + 438 WP_274980586.1 hypothetical protein -
PUW42_RS05660 (PUW42_05660) 1192473..1192733 + 261 WP_274980587.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PUW42_RS05665 (PUW42_05665) 1192720..1192998 + 279 WP_274980588.1 type II toxin-antitoxin system YafQ family toxin Toxin
PUW42_RS05670 (PUW42_05670) 1193035..1193397 - 363 WP_274980589.1 HNH endonuclease signature motif containing protein -
PUW42_RS05675 (PUW42_05675) 1193378..1193644 - 267 WP_101659814.1 hypothetical protein -
PUW42_RS05680 (PUW42_05680) 1193647..1194057 - 411 WP_101659816.1 sigma-70 family RNA polymerase sigma factor -
PUW42_RS05685 (PUW42_05685) 1194075..1194299 - 225 WP_274980590.1 helix-turn-helix transcriptional regulator -
PUW42_RS05690 (PUW42_05690) 1194296..1194937 - 642 WP_274980591.1 hypothetical protein -
PUW42_RS05695 (PUW42_05695) 1194990..1195556 - 567 WP_274980592.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1166223..1209162 42939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10957.74 Da        Isoelectric Point: 8.4650

>T272753 WP_274980588.1 NZ_CP118095:1192720-1192998 [Aerococcus christensenii]
MLKVEQSSEFIKHLKKYVKKHYDMEKLHRAVQALVKQDEQLLKTKYKDHSLNGQLQGLRELHIEGDWLLIYKIDHGKLIL
YLLDTGSHDDLF

Download         Length: 279 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9967.26 Da        Isoelectric Point: 4.4230

>AT272753 WP_274980587.1 NZ_CP118095:1192473-1192733 [Aerococcus christensenii]
MTNSTVTVRMDSKLKEDTREILDSLGLDFSAAINIYFKQINMKQGLPFEIKCSGLQQTLDDIKNGNSMTFENEKDWWKWV
TENVES

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References