Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1172330..1172813 Replicon chromosome
Accession NZ_CP118095
Organism Aerococcus christensenii strain VSI03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PUW42_RS05560 Protein ID WP_274980572.1
Coordinates 1172330..1172596 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUW42_RS05565 Protein ID WP_274980573.1
Coordinates 1172586..1172813 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW42_RS05530 (PUW42_05530) 1167833..1168702 - 870 WP_274980566.1 GH25 family lysozyme -
PUW42_RS05535 (PUW42_05535) 1168763..1168966 - 204 WP_274980567.1 phage holin -
PUW42_RS05540 (PUW42_05540) 1168967..1169260 - 294 WP_274980568.1 hypothetical protein -
PUW42_RS05545 (PUW42_05545) 1169276..1170106 - 831 WP_274980569.1 hypothetical protein -
PUW42_RS05550 (PUW42_05550) 1170111..1170419 - 309 WP_274980570.1 hypothetical protein -
PUW42_RS05555 (PUW42_05555) 1170397..1172280 - 1884 WP_274980571.1 gp58-like family protein -
PUW42_RS05560 (PUW42_05560) 1172330..1172596 - 267 WP_274980572.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUW42_RS05565 (PUW42_05565) 1172586..1172813 - 228 WP_274980573.1 DUF6290 family protein Antitoxin
PUW42_RS05570 (PUW42_05570) 1172918..1173865 - 948 WP_274980574.1 hypothetical protein -
PUW42_RS05575 (PUW42_05575) 1173865..1175364 - 1500 WP_274980575.1 hypothetical protein -
PUW42_RS05580 (PUW42_05580) 1175365..1177236 - 1872 WP_274980576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1166223..1209162 42939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10471.58 Da        Isoelectric Point: 10.5934

>T272752 WP_274980572.1 NZ_CP118095:c1172596-1172330 [Aerococcus christensenii]
MTYRLVLSKRARKQLKKMDRHVAYMLAKYMKKQLDGLSDPRIYGKALVGDKTGLWRYRLGDYRVICEIKDEQLVILALEI
GHRKLIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8725.68 Da        Isoelectric Point: 3.8829

>AT272752 WP_274980573.1 NZ_CP118095:c1172813-1172586 [Aerococcus christensenii]
MAVVSLRLNETEERTFRDYAKLTGKTLSELFKESLTQEIEDKLDYQVGLEALEEFQLDPTTYDIDEVIEELGHDL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References