272693

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 675443..676359 Replicon chromosome
Accession NZ_CP118021
Organism Bacillus spizizenii strain B-354

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag PT671_RS02980 Protein ID WP_003218453.1
Coordinates 675443..676189 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag PT671_RS02985 Protein ID WP_003218451.1
Coordinates 676189..676359 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT671_RS02955 670529..670675 - 147 WP_003218473.1 hypothetical protein -
PT671_RS02960 670776..671726 - 951 WP_003218472.1 ring-cleaving dioxygenase -
PT671_RS02965 672109..673425 + 1317 WP_003218471.1 serine/threonine exchanger -
PT671_RS02970 673702..674319 + 618 WP_003218470.1 DUF47 domain-containing protein -
PT671_RS02975 674332..675333 + 1002 WP_003218455.1 inorganic phosphate transporter -
PT671_RS02980 675443..676189 + 747 WP_003218453.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
PT671_RS02985 676189..676359 + 171 WP_003218451.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
PT671_RS02990 676445..676582 + 138 WP_136654612.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
PT671_RS02995 676620..677513 - 894 WP_003218449.1 N-acetylmuramoyl-L-alanine amidase -
PT671_RS03000 677526..677789 - 264 WP_003218447.1 phage holin -
PT671_RS03005 677802..678071 - 270 WP_003218444.1 hemolysin XhlA family protein -
PT671_RS03010 678124..678963 - 840 WP_003218443.1 hypothetical protein -
PT671_RS03015 679008..679172 - 165 WP_003218441.1 XkdX family protein -
PT671_RS03020 679169..679495 - 327 WP_003218439.1 XkdW family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29067.56 Da        Isoelectric Point: 4.6878

>T272693 WP_003218453.1 NZ_CP118021:675443-676189 [Bacillus spizizenii]
MLLFFQIMVWCIMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYDSSSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIEAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKNRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFIIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6545.55 Da        Isoelectric Point: 10.8401

>AT272693 WP_003218451.1 NZ_CP118021:676189-676359 [Bacillus spizizenii]
MERAFQNGCEPRAAKSFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References