272645

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 733143..733906 Replicon chromosome
Accession NZ_CP117988
Organism Vibrio campbellii strain 20220413_1

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag PUN50_RS03465 Protein ID WP_274290872.1
Coordinates 733143..733649 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag PUN50_RS03470 Protein ID WP_000212004.1
Coordinates 733640..733906 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUN50_RS03425 (PUN50_03425) 728217..728495 - 279 WP_000058216.1 helix-turn-helix transcriptional regulator -
PUN50_RS03430 (PUN50_03430) 728492..728815 - 324 WP_001896384.1 type II toxin-antitoxin system RelE/ParE family toxin -
PUN50_RS03435 (PUN50_03435) 728996..729277 + 282 WP_000433891.1 type IV conjugative transfer system protein TraL -
PUN50_RS03440 (PUN50_03440) 729274..729900 + 627 WP_274290870.1 TraE/TraK family type IV conjugative transfer system protein -
PUN50_RS03445 (PUN50_03445) 729884..730780 + 897 WP_274291235.1 type-F conjugative transfer system secretin TraK -
PUN50_RS03450 (PUN50_03450) 730783..732072 + 1290 WP_274290871.1 TraB/VirB10 family protein -
PUN50_RS03455 (PUN50_03455) 732147..732719 + 573 WP_024008834.1 type IV conjugative transfer system lipoprotein TraV -
PUN50_RS03460 (PUN50_03460) 732716..733102 + 387 WP_023584042.1 TraA family conjugative transfer protein -
PUN50_RS03465 (PUN50_03465) 733143..733649 - 507 WP_274290872.1 GNAT family N-acetyltransferase Toxin
PUN50_RS03470 (PUN50_03470) 733640..733906 - 267 WP_000212004.1 DUF1778 domain-containing protein Antitoxin
PUN50_RS03475 (PUN50_03475) 734275..734967 + 693 WP_274290873.1 DsbC family protein -
PUN50_RS03480 (PUN50_03480) 734967..737366 + 2400 WP_193284099.1 type IV secretion system protein TraC -
PUN50_RS03485 (PUN50_03485) 737359..737706 + 348 WP_015066569.1 hypothetical protein -
PUN50_RS03490 (PUN50_03490) 737690..738202 + 513 WP_258519357.1 S26 family signal peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 704190..774713 70523


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18308.03 Da        Isoelectric Point: 7.2132

>T272645 WP_274290872.1 NZ_CP117988:c733649-733143 [Vibrio campbellii]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKSQKRGTTRVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.48 Da        Isoelectric Point: 5.8580

>AT272645 WP_000212004.1 NZ_CP117988:c733906-733640 [Vibrio campbellii]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References