272638

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 1236109..1236586 Replicon chromosome
Accession NZ_CP117979
Organism Staphylococcus aureus strain B-41012

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag PT798_RS05895 Protein ID WP_000052076.1
Coordinates 1236109..1236297 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag PT798_RS05900 Protein ID WP_001059690.1
Coordinates 1236326..1236586 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT798_RS05865 1232144..1232620 + 477 WP_000824477.1 hypothetical protein -
PT798_RS05870 1232961..1233647 + 687 WP_001641381.1 thermonuclease family protein -
PT798_RS05875 1234004..1234204 + 201 WP_001059082.1 cold-shock protein -
PT798_RS05880 1234700..1234918 - 219 WP_000005887.1 hypothetical protein -
PT798_RS05885 1234980..1235264 - 285 WP_031590186.1 hypothetical protein -
PT798_RS05890 1235352..1235921 - 570 WP_001106652.1 lipoprotein N-acylation protein LnsA -
PT798_RS05895 1236109..1236297 - 189 WP_000052076.1 hypothetical protein Toxin
PT798_RS05900 1236326..1236586 - 261 WP_001059690.1 hypothetical protein Antitoxin
PT798_RS05905 1236927..1237130 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
PT798_RS05910 1237127..1237363 - 237 WP_000368687.1 hypothetical protein -
PT798_RS05915 1237588..1238169 + 582 WP_001140697.1 histidine phosphatase family protein -
PT798_RS05920 1238242..1238859 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
PT798_RS05925 1239015..1239509 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
PT798_RS05930 1239908..1240330 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
PT798_RS05935 1240478..1241194 + 717 WP_031589686.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T272638 WP_000052076.1 NZ_CP117979:c1236297-1236109 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT272638 WP_001059690.1 NZ_CP117979:c1236586-1236326 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References