Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 291960..292552 Replicon chromosome
Accession NZ_CP117968
Organism Allobacillus halotolerans strain BCRC 17939

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PT602_RS01710 Protein ID WP_216687588.1
Coordinates 292229..292552 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PT602_RS01705 Protein ID WP_216687582.1
Coordinates 291960..292229 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT602_RS01690 287756..287953 - 198 WP_216687579.1 hypothetical protein -
PT602_RS01695 288204..289571 + 1368 WP_216687580.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
PT602_RS01700 289960..291399 + 1440 WP_216687581.1 DUF4901 domain-containing protein -
PT602_RS01705 291960..292229 + 270 WP_216687582.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PT602_RS01710 292229..292552 + 324 WP_216687588.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PT602_RS01715 292605..292823 - 219 WP_246569289.1 hypothetical protein -
PT602_RS01720 292994..293098 - 105 WP_144161970.1 YjcZ family sporulation protein -
PT602_RS01725 293450..294913 + 1464 WP_216687583.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
PT602_RS01730 295069..295749 + 681 WP_216687584.1 hypothetical protein -
PT602_RS01735 295733..297439 + 1707 WP_216687585.1 GMC family oxidoreductase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-106)

Antitoxin

Antitoxin PemI-like

(12-89)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11995.83 Da        Isoelectric Point: 7.8563

>T272572 WP_216687588.1 NZ_CP117968:292229-292552 [Allobacillus halotolerans]
MEVPDKGDLIYLNFSPQSGHEQSGHRPAIVLSPKLFNQNTFLIACPITNQEKGYPFEVKIPSGLKVKGVILTDQIRSVEW
RSRNVKIVDQAPAETTDECLKKIATFL

Download         Length: 324 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10119.54 Da        Isoelectric Point: 9.6261

>AT272572 WP_216687582.1 NZ_CP117968:291960-292229 [Allobacillus halotolerans]
MTKESKGRIKITTKVQKWGNSLAVRIPSTVSNQLSIEQGSEVEIEVEAHSLKITPKKKEYTLEELMSQVTPENRHEKVDW
GKPKGSEAW

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References