Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 222132..222763 Replicon chromosome
Accession NZ_CP117968
Organism Allobacillus halotolerans strain BCRC 17939

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PT602_RS01320 Protein ID WP_144089539.1
Coordinates 222413..222763 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PT602_RS01315 Protein ID WP_144089538.1
Coordinates 222132..222407 (+) Length 92 a.a.

Genomic Context

PT602_RS01295PT602_RS01300PT602_RS01305PT602_RS01310PT602_RS01315PT602_RS01320PT602_RS01325PT602_RS01330PT602_RS01335PT602_RS01340PT602_RS01345PT602_RS01350PT602_RS01355
Location: 217238..218593 (1356 bp)
Type: Others
Protein ID: WP_212371692.1
Location: 218719..219087 (369 bp)
Type: Others
Protein ID: WP_144162546.1
Location: 219252..220274 (1023 bp)
Type: Others
Protein ID: WP_216687950.1
Location: 220864..221997 (1134 bp)
Type: Others
Protein ID: WP_216687949.1
Location: 222132..222407 (276 bp)
Type: Antitoxin
Protein ID: WP_144089538.1
Location: 222413..222763 (351 bp)
Type: Toxin
Protein ID: WP_144089539.1
Location: 223025..223900 (876 bp)
Type: Others
Protein ID: WP_144162552.1
Location: 223906..224265 (360 bp)
Type: Others
Protein ID: WP_246569343.1
Location: 224265..224666 (402 bp)
Type: Others
Protein ID: WP_144162556.1
Location: 224680..225693 (1014 bp)
Type: Others
Protein ID: WP_216687947.1
Location: 225758..226084 (327 bp)
Type: Others
Protein ID: WP_216687946.1
Location: 226084..226563 (480 bp)
Type: Others
Protein ID: WP_216687945.1
Location: 226535..227323 (789 bp)
Type: Others
Protein ID: WP_216687944.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PT602_RS01295217238..218593+1356WP_212371692.1IS1182 family transposase-
PT602_RS01300218719..219087+369WP_144162546.1holo-ACP synthase-
PT602_RS01305219252..220274+1023WP_216687950.1outer membrane lipoprotein carrier protein LolA-
PT602_RS01310220864..221997+1134WP_216687949.1alanine racemase-
PT602_RS01315222132..222407+276WP_144089538.1antitoxinAntitoxin
PT602_RS01320222413..222763+351WP_144089539.1type II toxin-antitoxin system PemK/MazF family toxinToxin
PT602_RS01325223025..223900+876WP_144162552.1STAS domain-containing protein-
PT602_RS01330223906..224265+360WP_246569343.1STAS domain-containing protein-
PT602_RS01335224265..224666+402WP_144162556.1anti-sigma regulatory factor-
PT602_RS01340224680..225693+1014WP_216687947.1PP2C family protein-serine/threonine phosphatase-
PT602_RS01345225758..226084+327WP_216687946.1STAS domain-containing protein-
PT602_RS01350226084..226563+480WP_216687945.1anti-sigma B factor RsbW-
PT602_RS01355226535..227323+789WP_216687944.1RNA polymerase sigma factor SigB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--217238..2185931355


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13036.08 Da        Isoelectric Point: 5.1239

>T272571 WP_144089539.1 NZ_CP117968:222413-222763 [Allobacillus halotolerans]
MYVKRGDVFYADLTPVVGSEQGGVRPVLIIQNNIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAEKYHFEKNSVILLEQI
RTIDKQRLTDKLTTLDEFLMNQVDEALQISLGLIDL

Download         Length: 351 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10442.72 Da        Isoelectric Point: 4.5082

>AT272571 WP_144089538.1 NZ_CP117968:222132-222407 [Allobacillus halotolerans]
MSNTSKEIVVELPLSLVNECDHMVEEHDIDRNTLFHQAISAYIKEEKNRKIKESMRRGYLEMKSINLDIASEAFQAEEEA
DTTLERSVSGV

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References