Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 222132..222763 Replicon chromosome
Accession NZ_CP117968
Organism Allobacillus halotolerans strain BCRC 17939

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag PT602_RS01320 Protein ID WP_144089539.1
Coordinates 222413..222763 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PT602_RS01315 Protein ID WP_144089538.1
Coordinates 222132..222407 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PT602_RS01295 217238..218593 + 1356 WP_212371692.1 IS1182 family transposase -
PT602_RS01300 218719..219087 + 369 WP_144162546.1 holo-ACP synthase -
PT602_RS01305 219252..220274 + 1023 WP_216687950.1 outer membrane lipoprotein carrier protein LolA -
PT602_RS01310 220864..221997 + 1134 WP_216687949.1 alanine racemase -
PT602_RS01315 222132..222407 + 276 WP_144089538.1 antitoxin Antitoxin
PT602_RS01320 222413..222763 + 351 WP_144089539.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PT602_RS01325 223025..223900 + 876 WP_144162552.1 STAS domain-containing protein -
PT602_RS01330 223906..224265 + 360 WP_246569343.1 STAS domain-containing protein -
PT602_RS01335 224265..224666 + 402 WP_144162556.1 anti-sigma regulatory factor -
PT602_RS01340 224680..225693 + 1014 WP_216687947.1 PP2C family protein-serine/threonine phosphatase -
PT602_RS01345 225758..226084 + 327 WP_216687946.1 STAS domain-containing protein -
PT602_RS01350 226084..226563 + 480 WP_216687945.1 anti-sigma B factor RsbW -
PT602_RS01355 226535..227323 + 789 WP_216687944.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 217238..218593 1355


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13036.08 Da        Isoelectric Point: 5.1239

>T272571 WP_144089539.1 NZ_CP117968:222413-222763 [Allobacillus halotolerans]
MYVKRGDVFYADLTPVVGSEQGGVRPVLIIQNNIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAEKYHFEKNSVILLEQI
RTIDKQRLTDKLTTLDEFLMNQVDEALQISLGLIDL

Download         Length: 351 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10442.72 Da        Isoelectric Point: 4.5082

>AT272571 WP_144089538.1 NZ_CP117968:222132-222407 [Allobacillus halotolerans]
MSNTSKEIVVELPLSLVNECDHMVEEHDIDRNTLFHQAISAYIKEEKNRKIKESMRRGYLEMKSINLDIASEAFQAEEEA
DTTLERSVSGV

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References